Acute Fetomaternal Hemorrhage Confirmed by Maternal Alfa-Fetoprotein in Monochorionic Diamniotic Neonates under 1,500 g

Yoo, Chaeri; Han, Song; Jeong, Hyemi; Heo, Ju Sun; Lee, Hyun-Seung; Ji-Hyun, Jeon

doi:10.5385/nm.2020.27.4.187

Cited by 1 publication

(2 citation statements)

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“…The authors found a similar incidence of large FMH in singleton and multiple pregnancies [ 25 ]. Moreover, several case reports presented different outcomes [ 2 , 3 , 12 , 26 , 27 , 28 ]. In all the abovementioned published studies, the incidence of a significant FMH was analyzed.…”

Section: Discussionmentioning

confidence: 99%

“…Different methods (flow cytometry tests, the microscopic Kleihauer-Betke method, serological agglutination test, high-performance liquid chromatography) were introduced for the measurement of the rate of fetal cells in maternal circulation [ 10 ]. Few reports are available on the analysis and comparison of FMT in singleton and twin pregnancies, and their findings are inconclusive [ 3 , 4 , 11 , 12 , 13 ].…”

Section: Introductionmentioning

confidence: 99%

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Is Feto-Maternal Transfusion after Cesarean Delivery Different in Singleton and Twin Pregnancy?

Stachurska-Skrodzka,

Mielecki,

Fijałkowska

et al. 2024

JCM

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Background: The aim of the study was to investigate if feto-maternal transfusion was related to the size of the fetal-maternal interface, and, therefore, was larger in twin pregnancy in comparison with singleton pregnancy. Methods: Blood samples from women with singleton (n = 11), and monochorionic (n = 11) and dichorionic (n = 13) twin gestations were tested. Flow cytometry tests with hemoglobin F, glycophorin A, and hemoglobin F and carbonic anhydrase simultaneous staining were used to detect fetal red blood cells and maternal F cells. Results: In all cases, the volume of feto-maternal transfusion was estimated to be low. The highest rate of fetal red blood cells in the maternal circulation was observed in the blood of women with dichorionic twin gestations both before and after delivery. An increase in fetal red blood cells was observed after cesarean section in singletons and twins. The median rate of maternal F cells was 2.23% in singleton, 2.1% in monochorionic and 3.95% in dichorionic pregnancy. Conclusions: Feto-maternal transfusion during pregnancy may be related to the multiplicity and chorionicity of pregnancy.

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