“…The onset age in children is mostly 3–6 years, 7 and typical manifestations include fever, tonsillar exudates, nasal obstruction, eyelid edema, lymphadenopathy, hepatosplenomegaly, and rashes. Some children may present with serious complications, such as airway obstruction, thrombocytopenia, rhabdomyolysis, splenic infarction, meningitis, and liver failure, 8,9 and such complications are more likely to occur in immunocompromised children. Hence, when serious complications occur, it is critical to determine whether the child has immunodeficiency 10,11 …”