Acute Epigastric Abdominal Pain Post-Gastric Polypectomy

Hashash, Jana G.; El-Haddad, Aline; Barada, Kassem

doi:10.1053/j.gastro.2017.05.061

Cited by 2 publications

(1 citation statement)

References 3 publications

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“…Patients undergoing endoscopic submucosal dissection (ESD) for early esophageal cancer commonly experience substantial postoperative pain [10] , necessitating effective pain management strategies. In this study, we explored the analgesic e cacy and side effects of opioid analgesics, speci cally oxycodone and sufentanil, during ESD surgery.…”

Section: Discussionmentioning

confidence: 99%

A Comparative Analysis of Transitional Analgesia with Oxycodone and Sufentanil in Patients with Early Esophageal Carcinoma Undergoing Endoscopic Submucosal Dissection

Gu,

Chen,

et al. 2024

Preprint

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Background: Postoperative pain management is a critical consideration in patients undergoing endoscopic submucosal dissection (ESD) for early esophageal carcinoma. Conventional transitional analgesia methods involve the administration of either oxycodone or sufentanil. However, the efficacy of oxycodone in the context of patients with early esophageal carcinoma undergoing ESD under general anesthesia remains uncertain. This study aims to compare the postoperative analgesic effects of oxycodone and sufentanil in patients undergoing ESD for early esophageal carcinoma patients under general anesthesia. Methods: In this randomized double-blind controlled study, 86 patients scheduled for ESD surgery under general anesthesia were enrolled. They were randomly assigned to the oxycodone group (O group, n = 29), sufentanil group (S group, n = 30), or normal saline group (N group, n = 26) using a double-blind method. Thirty minutes before the end of the surgery, patients in the O group received oxycodone (0.1 mg/kg), those in the S group received sufentanil (0.1 μg/kg), and those in the N group received an identical volume of normal saline. Various parameters, including general patient conditions, intraoperative anesthetic medication, vital sign variations throughout the perioperative period, postoperative recovery duration, decannulation time, and adverse reactions during the recovery period were meticulously recorded. Visual Analog Scale (VAS) scores at rest and during movement at 0 h, 12 h, and 24 h post-surgery, along with the incidence of pain relief and malignant vomiting, were also documented. Results: No statistically significant differences were observed in general patient conditions, intraoperative anesthetic dosages, or vital sign changes among the three groups. However, patients in the O group exhibited significantly prolonged recovery and decannulation times compared to the S and N groups,without impeding overall recovery. Statistically significant differences in adverse reactions during the recovery period were observed (P<0.05). Furthermore, patients in the O group demonstrated decreased VAS scores at 0 h, 12 h, and 24 h post-surgery, regardless of rest or movement, compared to the S and N groups. Although VAS scores in the S group were significantly reduced at postoperative 0 h and 12 h at rest compared to the N group, no significant differences were noted in the reduction of VAS scores during movement. The incidence of severe vomiting did not significantly differ among the three postoperative groups. Conclusion: When compared with sufentanil, oxycodone exhibited more prolonged and comprehensive analgesic effects in patients undergoing esophageal ESD under general anesthesia, with no significant side effects. These findings contribute to our understanding of transitional analgesia strategies in this specific patient population.

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Section: Discussionmentioning

confidence: 99%

A Comparative Analysis of Transitional Analgesia with Oxycodone and Sufentanil in Patients with Early Esophageal Carcinoma Undergoing Endoscopic Submucosal Dissection

Gu,

Chen,

et al. 2024

Preprint

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Pain in the epigastral area: current aspects of differential diagnosis

Trukhan,

Tarasova

2024

Medicinskij sovet

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Epigastric pain can have a variety of etiologies, including not only diseases of the upper gastrointestinal tract (GIT): gastroesophageal reflux disease, hiatal hernia, gastritis and duodenitis, gastric and/or duodenal ulcers, polyps and stomach cancer, functional dyspepsia, but also other gastrointestinal diseases, somatic diseases of other organs and systems, vascular pathology, infections and invasions, medications and a number of other reasons. More than 10 years have passed since the publication of our previous article on the issues of differential diagnosis of pain in the stomach. In the Elibrary.ru information base, both in the period of time preceding the publication and to this day, we have not found similar publications. This explains its placement in full or in fragments on specialized gastroenterological sites and guidelines for differential diagnosis in gastroenterology. Over the past 10 years, new consensuses and clinical recommendations have been published on diseases and conditions associated with epigastric pain, and the number of publications on other diseases and conditions that were previously considered very rare, but which today must be taken into account when carrying out differential diagnosis, has increased. Several foreign publications on the problem in recent years were found in the PubMed electronic database. In this regard, we consider it appropriate to consider the current aspects of the differential diagnosis of epigastric pain from the perspective of today. The list of diseases and conditions presented in the review, in which epigastric pain occurs in the clinical picture, indicates that the differential diagnosis of this syndrome is an interdisciplinary problem and is of interest not only to the gastroenterologist and therapist, but also to doctors of other specialties.

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Acute Epigastric Abdominal Pain Post-Gastric Polypectomy

Cited by 2 publications

References 3 publications

A Comparative Analysis of Transitional Analgesia with Oxycodone and Sufentanil in Patients with Early Esophageal Carcinoma Undergoing Endoscopic Submucosal Dissection

A Comparative Analysis of Transitional Analgesia with Oxycodone and Sufentanil in Patients with Early Esophageal Carcinoma Undergoing Endoscopic Submucosal Dissection

Pain in the epigastral area: current aspects of differential diagnosis

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