Acute Effects of Physical Exercise at different intensities on Inflammatory Markers in Obese Adolescents

Santos, Gizelly; Faria, Wayne Ferreira; Sasaki, Jeffer Eidi; Elias, Rui Marques; Neto, Antônio Stabelini

doi:10.4025/jphyseduc.v30i1.3014

Cited by 7 publications

(5 citation statements)

References 19 publications

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“…This study revealed that the TNF-α control group had more significant decrease compared to the experimental group. This finding is in accordance with the previous study by Dos Santos (2019) on obese female adolescents with sedentary behavior who were given a 30-minute intervention with an intensity equivalent to 75% of their treadmill VO2max. The insignificant decrease in TNF-α is associated with exercise intensity that is probably too high for the subjects.…”

Section: Discussionsupporting

confidence: 93%

Response of TNF-α Levels and Blood Glucose Levels after Acute High-Intensity Intermittent Exercise in Overweight Women

Devi,

Rejeki,

Argarini

et al. 2023

Retos

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Sedentary behavior is a lifestyle that plays a role in the pathophysiology of obesity or overweight. TNF-α is an inflammatory cytokine that can affect glucose metabolism and can trigger insulin resistance. Acute HIIE is exercise with alternating periods of high-intensity exercise and periods of active recovery. The purpose of this study was to examine the changes of TNF-α and blood glucose levels after acute HIIE in overweight women. Subjects were overweight women, divided into 2 groups (K1=control group and K2=experimental group; n=7) with a body mass index between 23.00 and up to 24.99 kg/m2. The acute protocol of HIIE with ergocycle consisted of a 3-minute warm-up (starting at 40 rpm), core exercise for 60 s at 80%-90% of HRmax, interspersed with 60 s of active recovery (40 rpm), and cool-down for 2 minutes. The pre-test was performed before treatment and the post-test was performed 60 minutes after treatment. Serum TNF-α levels were measured by the human enzyme-linked immunosorbent assay (ELISA) method. Blood glucose levels were taken by finger prick. The result showed that the change of TNF-α (the difference of pre and post) was a significant decrease in the K1 and K2 group (p<0.05), and the K2 group less decrease compared to K1. Blood glucose was significant in the K1 group (p<0.05). This study can be concluded that the TNF-α level is unchanged and the blood glucose levels is increase in overweight women with sedentary behavior performing acute HIIE. Keywords: Interval exercise; TNF-α; Glucose; Overweight; sedentary lifestyle

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Section: Discussionsupporting

confidence: 93%

Response of TNF-α Levels and Blood Glucose Levels after Acute High-Intensity Intermittent Exercise in Overweight Women

Devi,

Rejeki,

Argarini

et al. 2023

Retos

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“…Muñoz-Cánoves et al (2013) stated that IL-6 signalling has been associated with stimulation of muscle hypertrophy and myogenesis through regulation of the proliferative capacity of muscle stem cells. Santos et al (2019) in his research using obese adolescent subjects who were given an exercise intervention for 30 min, stated that there was a significant increase in IL-6 levels (P≤0.05). Similar results with this study in relation to TNF-α parameters have been carried out by Mauer et al (2014) who demonstrated a low-grade inflammatory effect by administering a low dose of Escherichia coli endotoxin (0.06 ng/kg) to healthy volunteers, who were randomised to rest or exercise prior to infusion.…”

Section: Discussionmentioning

confidence: 99%

Inflammatory markers in response to interval and continuous exercise in obese women

Andarianto

Rejeki

Sakina

et al. 2022

CEP

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Obesity is strongly associated with the degree of inflammation characterised by proinflammatory cytokines, such as tumour necrosis factor-α (TNF-α). Lifestyle modification with exercise is the right strategy because it can stimulate interleukin 6 (IL-6) secretion which acts as an anti-inflammatory. This study aimed to analyse the response of interval and continuous exercise to inflammatory markers in obese women. Twenty-four women participated in this study and were randomly divided into 3 groups: CONG (n=8, control group without any intervention): MCEG (n=8, continuous exercise group) and MIEG (n=8, interval exercise group). ELISA was used to measure the levels of IL-6 and TNF-α, pre-exercise and post-exercise. The data were analysed using the paired sample t-test. The mean levels of TNF-α, pre-exercise and post-exercise, were 19.35±2.73 vs 19.36±2.23 pg/ml (P=0.989) in CONG, 19.42±2.79 vs 16.63±0.82 pg/ml (P=0.017) in MCEG, and 19.46±3.08 vs 16.96±2.11 pg/ml (P=0.079) in MIEG. Mean levels of IL-6, pre-exercise and post-exercise, were 7.56±2.88 vs 7.66±4.12 pg/ml (P=0.957) for CONG, 7.68±3.41 vs 13.97±2.38 pg/ml (P=0.001) for MCEG, and 7.78±1.99 vs 13.66±3.55 pg/ml (P=0.001) for MIEG. We concluded that interval and continuous exercise decreased pro-inflammatory and increased anti-inflammatory cytokines.

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“…The response of vascular inflammatory markers to aerobic exercise depends on exercise duration and intensity. Although a single bout of exercise increased circulating levels of IL-6, -8, -10, tumor necrosis factor-α (TNF-α) and C-reactive protein (CRP) [47,48], regular aerobic exercise was associated with decrease in serum concentration of inflammatory markers. A 2-week voluntary wheel running of old mice reduced activation of the proinflammatory transcription factor NF-κB, diminished aortic expression of the proinflammatory cytokines IL-1 and IL-6 and ameliorated NO-mediated endothelium-dependent dilation [49], and an 8-week running protocol in obese rats decreased plasma TNF-α, increased e-NOS protein expression and improved endothelium-dependent relaxation [50].…”

Section: Endothelial Dysfunction and Aerobic Exercisementioning

confidence: 99%

Vascular Ageing and Aerobic Exercise

Kozàkovà

Palombo

2021

IJERPH

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Impairment of vascular function, in particular endothelial dysfunction and large elastic artery stiffening, represents a major link between ageing and cardiovascular risk. Clinical and experimental studies identified numerous mechanisms responsible for age-related decline of endothelial function and arterial compliance. Since most of these mechanisms are related to oxidative stress or low-grade inflammation, strategies that suppress oxidative stress and inflammation could be effective for preventing age-related changes in arterial function. Indeed, aerobic physical activity, which has been shown to improve intracellular redox balance and mitochondrial health and reduce levels of systemic inflammatory markers, also improves endothelial function and arterial distensibility and reduces risk of cardiovascular diseases. The present paper provides a brief overview of processes underlying age-related changes in arterial function, as well as the mechanisms through which aerobic exercise might prevent or interrupt these processes, and thus attenuate vascular ageing.

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Acute Effects of Physical Exercise at different intensities on Inflammatory Markers in Obese Adolescents

Cited by 7 publications

References 19 publications

Response of TNF-α Levels and Blood Glucose Levels after Acute High-Intensity Intermittent Exercise in Overweight Women

Response of TNF-α Levels and Blood Glucose Levels after Acute High-Intensity Intermittent Exercise in Overweight Women

Inflammatory markers in response to interval and continuous exercise in obese women

Vascular Ageing and Aerobic Exercise

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