Acute Effects of Passive Smoking on Left Ventricular Systolic and Diastolic Function in Healthy Volunteers

Doğan, Ali; Yarlıoğlueş, Mikail; Gül, İbrahim; Kaya, Mehmet; Özdoğru, İbrahіm; Kalay, Nihat; İnanç, Mehmet Tuğrul; Ozdogru, Mehtap; Ardıç, İdris; Doğdu, Orhan; Eryol, Namık Kemal; Ergin, Ali; Oğuzhan, Abdurrahman

doi:10.1016/j.echo.2010.10.019

Cited by 20 publications

(25 citation statements)

References 31 publications

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“…38 We have previously shown that color TDI demonstrated impaired diastolic function independently from hemodynamic changes, including heart rate and blood pressure. 4 …”

Section: Discussionmentioning

confidence: 99%

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Dose-Dependent Acute Effects of Passive Smoking on Left Ventricular Cardiac Functions in Healthy Volunteers

Yarlıoğlueş¹,

Kaya²,

Ardıç

et al. 2012

Journal of Investigative Medicine

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“…38 We have previously shown that color TDI demonstrated impaired diastolic function independently from hemodynamic changes, including heart rate and blood pressure. 4 …”

Section: Discussionmentioning

confidence: 99%

“…3 We have previously shown that acute exposure to passive smoking impaired left ventricular diastolic functions immediately in healthy volunteers. 4 …”

mentioning

confidence: 99%

Dose-Dependent Acute Effects of Passive Smoking on Left Ventricular Cardiac Functions in Healthy Volunteers

Yarlıoğlueş¹,

Kaya²,

Ardıç

et al. 2012

Journal of Investigative Medicine

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“…Cigarette smoking is a common risk factor for cardiovascular diseases (12)(13)(14). Cardiovascular mortality has been shown to be reduced by 36% after cessation of smoking (15)(16)(17).…”

Section: Discussionmentioning

confidence: 99%

Short-term effects of varenicline therapy on homogeneity of heart rate, atrioventricular conduction and ventricular repolarization

KaraveliogAAlu¹,

Karapınar²

2015

Curr Res Cardiol

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69Y Karavelioğlu, H Karapınar, M Kalçık, Z Küçükdurmaz, S Özkurt, T Sarak. Short-term effects of varenicline therapy on homogeneity of heart rate, atrioventricular conduction and ventricular repolarization. Curr Res Cardiol 2015;2(2):69-72.BaCKgRound: The effects of varenicline, an effective drug for smoking cessation, on atrioventricular and ventricular conductance remain unknown. oBjeCTive: To evaluate the effects of varenicline on heart rate, PR interval, QT interval and QT dispersion (QTd). MeTHodS: A total of 60 smokers were prospectively enrolled in the present study. Twelve-lead electrocardiogram recordings were obtained for all subjects before and on the 15th day of drug administration. Electrocardiograms were recorded at an amplitude of 20 mm/mV and a sweep speed of 50 mm/s. ReSulTS:The mean (± SD) age of the volunteers was 38±10 years. Thirtyfour (57%) were male. Fourteen (23%) had hypertension, eight (13%) had diabetes and six (10%) had chronic obstructive pulmonary disease. The mean heart rate was 74.7±13.3 beats/min, and mean systolic and diastolic blood pressures on admission were 122.3±14.3 mmHg and 76.5±10.2 mmHg, respectively. Heart rate, and systolic and diastolic blood pressures did not change with varenicline treatment. Varenicline treatment resulted in limited prolongation in PR interval, which appropached significance (163.5±18.3 ms versus 168.2±17.9 ms; P=0.053), while RR interval (796.3±117.4 ms versus 798.3±123.7 ms; P=0.926), QT interval (384.1±17.5 ms versus 383.4±20.9 ms; P=0.852) and QTd (52.6±14.9 ms versus 52.2±14.9 ms; P=0.919) were not significantly changed. ConCluSion: Varenicline had a limited effect on atrioventricular conduction, while it had no effect on heart rate, QT interval and QTd. Further studies are needed to prove the effects of varenicline on the conduction system of the heart, especially on PR interval.

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“…Так, в исследовании А. Dogan [7] диастолическая функция ЛЖ существенно изменилась сразу после пассивного куре-ния. Трансмитральная волна Е (0,89±0,12 против 0,70±0,14 м/с, р=0,001), легочная венозная D волна (0,52±0,12 против 0,49±0,13 м/с, р=0,01) и трансмитральное соотношение E/А (1,79±0,48 против 1,47±0,32, р=0,001) снизились, в то время как скоростные и интегральные показатели трансмитраль-ного потока не изменились.…”

Section: структурноunclassified

Geometric and structural-functional transformation of the heart in patients with hypertension stage II with smoking status

Syvolap¹,

Poznanska²,

Vizir³

2014

ZMJ

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Показали особливості структурно-геометричного та функціонального стану міокарда у хворих на гіпертонічну хворобу II стадії залежно від статусу курця. Паління у цієї групи хворих асоціюється з більшим ступенем дилатації лівого передсердя, гіпертрофії міокарда лівого шлуночка, його діастолічного напруження, а також порушень процесу діастолічного наповнення. Geometric and structural-functional transformation of the heart in patients with hypertension stage II with smoking status V. V. Syvolap, K. O. Poznanska, O. V. VizirPeculiarities of structure-geometric and functional state of the myocardium in patients with hypertension stage II depending on smoking status are still need to be studied. Smoking in this group of patients is associated with a greater degree of the left atrium dilatation, left ventricular hypertrophy, diastolic tension, as well as violations of the process of diastolic pressure.

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Acute Effects of Passive Smoking on Left Ventricular Systolic and Diastolic Function in Healthy Volunteers

Cited by 20 publications

References 31 publications

Dose-Dependent Acute Effects of Passive Smoking on Left Ventricular Cardiac Functions in Healthy Volunteers

Dose-Dependent Acute Effects of Passive Smoking on Left Ventricular Cardiac Functions in Healthy Volunteers

Short-term effects of varenicline therapy on homogeneity of heart rate, atrioventricular conduction and ventricular repolarization

Geometric and structural-functional transformation of the heart in patients with hypertension stage II with smoking status

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