Acute effects of benzodiazepines on operant behavior and in vivo receptor binding in mice

Aggressive behavior as a reinforcer in mice: activation by allopregnanolone

“…These results are also typical of benzodiazepines, other GABA A receptor positive modulators (Cook and Kelleher 1962;Richelle et al 1962;Sanger and Blackman 1981;Shannon and Thompson 1985;Wettstein and Spealman 1988;Burke et al 1994). The 10.0 mg/kg dose also produced a small, but statistically significant increase in the low rate of responding in the inactive hole.…”