Acute effects of air pollution on ischaemic stroke onset and deaths: a time-series study in Changzhou, China

Hua, Dong; Yu, Yongquan; Shen, Yao; Lu, Yan; Chen, Zhiyong; Li, Guiying; Yao, Yao; Yao, Xingjuan; Wang, Shoulin; Zhang, Zhan

doi:10.1136/bmjopen-2017-020425

Cited by 43 publications

(45 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The size of association, varied considerably according to individual-specific characteristics including demographic, lifestyle, and medical history factors, ranging OR = 0.966 (95% CI 0.920-1.013) to 1.145 (95% CI 1.080-1.215) among Chinese adults. Dong et al (2018) determined that PM 2.5 can also moderate associations of stroke risk for other pollutants. To investigate the acute effect of NO 2 and SO 2 on IS and IS-related death in five urban districts in Changzhou between 2015 and 2016, they estimated the percentage change (95% CI) in daily IS counts and deaths with an IQR increase in air pollutant levels for different single or multiple lag days in both singlepollutant and two-pollutant models.…”

Section: Pm 25 and Stroke In Chinamentioning

confidence: 99%

“…Dong et al ( 2018 ) determined that PM 2.5 can also moderate associations of stroke risk for other pollutants. To investigate the acute effect of NO 2 and SO 2 on IS and IS-related death in five urban districts in Changzhou between 2015 and 2016, they estimated the percentage change (95% CI) in daily IS counts and deaths with an IQR increase in air pollutant levels for different single or multiple lag days in both single-pollutant and two-pollutant models.…”

Section: Pm 25 and Stroke In Chinamentioning

confidence: 99%

See 1 more Smart Citation

The contribution of PM2.5 to cardiovascular disease in China

Zhang

Routledge

2020

Environ Sci Pollut Res

View full text Add to dashboard Cite

China is experiencing rapid urbanization and industrialization with correspondingly high levels of air pollution. Although the harm of PM2.5 has been long reported, it is only quite recently that there is increasing concern in China for its possible adverse health effects on cardiovascular disease. We reviewed the epidemiologic evidence of potential health effects of PM2.5 on cardiovascular disease reported from recent studies in China (2013 onwards). There is clear evidence for the contribution of PM2.5 to cardiovascular outcomes, including mortality, ischemic heart disease, and stroke from studies based in various regions in China. This evidence adds to the global evidence that PM2.5 contributes to adverse cardiovascular health risk and highlights the need for improved air quality in China.

show abstract

Section: Pm 25 and Stroke In Chinamentioning

confidence: 99%

Section: Pm 25 and Stroke In Chinamentioning

confidence: 99%

The contribution of PM2.5 to cardiovascular disease in China

Zhang

Routledge

2020

Environ Sci Pollut Res

View full text Add to dashboard Cite

show abstract

“…These findings may have significant public health implications for the prevention of IS and IS-related deaths. The authors recommended further studies to validate their research 23 . In the study related to short-term exposure to ambient fine particulate matter (PM2,5 and PM10) and the risk of heart rhythm abnormalities and stroke, in case of stroke the authors found a stronger correlation between the number of hospitalizations and death cases and exposure to fine dust for ischaemic stroke than for haemorrhagic stroke.…”

Section: -57mentioning

confidence: 99%

Air Pollution: a New Risk Factor for Developing Stroke

Demarin¹,

Morović²,

Đerke³

2019

Rad Hrvatske akademije znanosti i umjetnosti

View full text Add to dashboard Cite

Many years scientist try to explore the connection between air pollution and its influence on human health and after numerous conducted researches they came up with the clear evidence that air pollution has a significant impact on overall health and especially on stroke. In the Global Burden of Disease Study, it has emerged as a significant contributor to the global stroke burden, especially in low-and middle-income countries. Furthermore, these and some other researches have suggested a closer link between air pollution and ischemic stroke, due to huge diversity of the results of numerous other studies, for drawing definitive conclusions, further research is still needed. Due to the complexity of stroke with its types and subtypes, the results of their reaction to air pollution differ. Some studies have shown the link between cardioembolic stroke and AP, others with SAH but not with intracerebral haemorrhage. There was a suggestion that nitrogen dioxide exposure might be associated with stroke caused by small vessel disease, while other studies are not reporting any association of AP and the risk of ischemic stroke. In some studies, AP was more affecting young adults and in some, it was more pronounced in women. Some studies reported a more clear link between AP and recent stroke in patients with other risk factors like diabetes and previous stroke. Studies have varied by the concentration and types of pollutants studied, which vary geographically, as well as by duration to AP exposure being short-or long-term, and in some studies being present only during warm seasons.Regulations have improved air quality in many countries in Europe and the United States, resulting in greater life expectancy, which highlights the continued importance of further efforts in that direction. Sažetak: Zagađenje Zraka: novootkriveni faktor riZika u raZvoju moždanog udaraVeć nekoliko godina znanstvenici pokušavaju istražiti povezanost zagađenja zraka i njegovog utjecaja na zdravlje ljudi, a nakon brojnih provedenih istraživanja došli su do jasnih dokaza da zagađenje zraka ima značajan utjecaj na cjelokupno zdravlje, s posebnim naglaskom na ravoj moždanog udara. U "Global Bourden of Disease" (szo)pokazalo se da zagađeni zrak značajno doprinosi globalnom opterećenju od moždanog udara, posebno u zemljama s niskim i srednjim dohotkom. Nadalje, ova i neka druga istraživanja sugeriraju blisku povezanost zagađenja zraka i ishemijskim moždanim udarom, dok zbog raznolikosti rezultata brojnih drugih studija, za donošenje konačnih zaključaka, potrebna su još daljnja istraživanja. Zbog složenosti moždanog udara s njegovim tipovima i podvrstama, rezultati njihove reakcije na onečišćenje zraka razlikuju se. Neke studije pokazuju vezu između kardioemboličkog moždanog udara i zagađenog zraka, druge sa subarahnoidalnim krvarenjem, ali ne i intracerebralnog krvarenjem. Bilo je nagovještaja i da je izlaganje dušičnom dioksidu povezano s moždanim udarom uzrokovanim bolešću malih žila, dok druge studije ne opisuju tu povezanost sa rizikom od ishemijskog m...

show abstract

“…However, in developing countries like China, the evidence is limited and very few studies [11] distinguished between ischemic and hemorrhagic stroke. Most studies only focused on ischemic stroke but the results have not been conclusive yet, with some finding evidence of a positive association [12] but not in other studies [13][14][15][16].…”

Section: Introductionmentioning

confidence: 98%

Association of short-term exposure to sulfur dioxide and hospitalization for ischemic and hemorrhagic stroke in Guangzhou, China

Shen

Yuan

et al. 2020

BMC Public Health

View full text Add to dashboard Cite

Background: In developing countries, ambient sulfur dioxide (SO 2 ) is a serious air pollutant concern, but there is no enough and consistent epidemiological evidence about its health effects on stroke hospitalization. Methods: We collected the daily air pollution data, meteorological data and number of daily hospital admissions for ischemic and hemorrhagic stroke, in Guangzhou from January 1st 2009 to December 31st 2014. Then we applied generalized additive model with a quasi-Poisson link to assess the relationship between short-term SO 2 exposure and the total number of hospital admissions for ischemic and hemorrhagic stroke. In addition, we evaluated the effect of ambient SO 2 by age (< 65 years and ≥ 65 years). Results: During the study period, a 24-h mean concentration of ambient SO 2 of 27.82 μg/m 3 , a total of 58,473 ischemic stroke and 9167 hemorrhagic stroke hospital admissions hospital were recorded. Ambient SO 2 was found to increase the risk for both ischemic and hemorrhagic stroke hospital admission in single pollutant model. The maximum value of percentage changes for ischemic and hemorrhagic stroke occurred in lag 0 day and lag 1 day, per 10 μg/m 3 increase in SO 2 concentrations was corresponded to a 1.27% (95% confidence interval (CI), 0.42-2.12%) and 1.55% (95%CI, 0.02-3.11%) increased risk, respectively. The association between SO 2 and ischemic stroke hospitalization was robust to two pollutant model, but for hemorrhagic stroke it's partially weakened after adjusting for co-pollutants. The effect of ambient SO 2 on ischemic stroke appeared to be greater for people < 65 years old, but null effect on hemorrhagic stroke was identified for both age groups. Conclusions: We found short-term exposure to ambient SO 2 may significantly increase the risks of hospitalization for ischemic stroke. The findings may contribute to a better understanding of the health effects of low-levels of SO 2 .

show abstract

Acute effects of air pollution on ischaemic stroke onset and deaths: a time-series study in Changzhou, China

Cited by 43 publications

References 40 publications

The contribution of PM2.5 to cardiovascular disease in China

The contribution of PM2.5 to cardiovascular disease in China

Air Pollution: a New Risk Factor for Developing Stroke

Association of short-term exposure to sulfur dioxide and hospitalization for ischemic and hemorrhagic stroke in Guangzhou, China

Contact Info

Product

Resources

About