Acute effects of air pollution on respiratory disease mortalities and outpatients in Southeastern China

Mo, Zhe; Fu, Qiang; Zhang, Lifang; Lyu, Danni; Mao, Guangming; Wu, Lizhi; Xu, Pingwei; Wang, Zhifang; Pan, Xuejiao; Chen, Zhijian; Wang, Xiaofeng; Lou, Xiaoming

doi:10.1038/s41598-018-19939-1

Cited by 58 publications

(49 citation statements)

References 33 publications

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“…Our previous study provided evidence that both the mortality rates and outpatient visits for RDs were signi cantly associated with air pollution among which PM 2.5 plays a crucial role in two typical cities (HZ and ZS) in Zhejiang Province [16]. In order to further investigate the effects of particulates with different diameters, more data with a longer period from six cities with different air conditions in Zhejiang Province were collected.…”

Section: Discussionmentioning

confidence: 99%

Association between ambient fine particulate matters and chronic obstructive pulmonary disease (COPD) mortality: an analysis in Southeastern China

Chen¹,

Fu²,

Mao³

et al. 2020

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Background: The objective of this study was to investigate the association between ambient particulate matters(PMs)and chronic obstructive pulmonary disease (COPD) mortality.Methods: Generalized Additive Mixed Model was employed to investigate the effects of ambient fine and coarse PMs on COPD mortality using 13,066 deaths from 2014 to 2016 among six cities in Zhejiang Province in Southeastern China.Results: The daily average death count due to COPD was 3, varying from 1 to 7among six cities. The daily 24-hour mean concentrations were diverse among cities, from 29.7 to 56.8 µg/m3 for PM2.5, 16.7 to 30.3 µg/m3 for PM2.5−10, and 50.3 to 87.1 µg/m3 for PM10, respectively. The analysis showed that daily exposure to PM2.5 and PM10 was associated with increased mortality due to COPD and that weak effects were observed between PM2.5−10 and COPD mortality.Conclusions: Our results provided evidence that the fine particles in air pollution have stronger functions on adverse health effects other than coarser particles in Southeastern China, which may be considered as a potential clinic target in PM-associated COPD.

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Section: Discussionmentioning

confidence: 99%

Association between ambient fine particulate matters and chronic obstructive pulmonary disease (COPD) mortality: an analysis in Southeastern China

Chen¹,

Fu²,

Mao³

et al. 2020

Preprint

Self Cite

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“…Atmospheric particulate matter (PM) can induce lung tissue damage through oxidative stress and pro-in ammatory factors [7]. Many epidemiological studies have proved that atmospheric pollutants are closely related to the occurrence and death of respiratory and cardiovascular diseases [8][9][10][11]. When it comes to pneumonia, a few previous investigations have found a correlation between atmospheric pollution concentration and hospitalization or emergency department (ED) visits for pneumonia in the mainland of China [12][13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Air Pollutants and Hospital Visits for Pneumonia: A Case-crossover Study in Qingdao, China.

Zhang

Cao

Wang

et al. 2020

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Background: Pneumonia is one of the principal reasons for incidence and death in the world. The former research mainly concentrated on specific sources of patients. Besides, due to the heterogeneity among regions, there are inconsistencies in the outcome of these surveys. To explore the significance of the relationship between atmospheric pollution and hospital visits for pneumonia under the climate and pollution conditions in Qingdao, we carried out this study.Methods: The medical records of pneumonia patients were gathered from the affiliated hospital of Qingdao University during Jan 1st, 2014, and Dec 31st,2018. Daily concentrations of PM2.5, PM10, SO2, NO2, as well as CO, were collected from the national air quality monitoring stations in Qingdao. Case-crossover design and conditional logistic regression were used to calculate these materials. A principal component analysis was used to solve the multicollinearity between atmospheric pollutants and investigate the relationship between various air pollutants and pneumonia occurs.Results: In the single pollutant model, with interquartile range increment of the density of PM2.5, PM10, SO2 and NO2 at the lag2 days, the odds ratio of hospital visits for pneumonia patients increased by 6.4% (95%CI, 2.3-10.7%), 7.7% (95%CI, 3.2-12.4%), 6.7% (95%CI, 1.0-12.7%), and 7.2% (95%CI, 1.1-13.5%). Stratified analysis showed that pollutants were more significant in the cold period. Besides, the impact of atmospheric particulates on different ages mainly occurs in the younger child. The odds ratio was 1.042 (95%CI, 1.2-7.2%) when the principal components of atmospheric pollutants were included in the conditional logistic model.Conclusion: Our study found a significant relationship between short-term uncovering to PM2.5, PM10, NO2, SO2, and hospital visits for pneumonia in Qingdao. The effect of atmospheric pollutants mainly arose in a cold period. Particulate matter might the principal reason in inducing hospital visits for pneumonia.

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“…Atmospheric particulate matter (PM) can induce lung tissue damage through oxidative stress and pro-in ammatory factors [7]. Numerous epidemiological studies have been carried out and proved that atmospheric pollutants are closely related to the occurrence and death of respiratory and cardiovascular diseases [8][9][10][11]. Regarding pneumonia, the previous animal experiments have con rmed a short-term exposure to air pollutants was capable of causing lung in ammation [12].…”

Section: Introductionmentioning

confidence: 99%

Ambient air pollutants and hospital visits for pneumonia: A case-crossover study in Qingdao, China.

Zhang

Cao

Wang

et al. 2020

Preprint

View full text Add to dashboard Cite

Background: Pneumonia is one of the principal reasons for incidence and death in the world. The former research mainly concentrated on specific sources of patients. Besides, due to the heterogeneity among regions, there are inconsistencies in the outcome of these surveys. To explore the significance of the relationship between atmospheric pollution and hospital visits for pneumonia under the climate and pollution conditions in Qingdao, we carried out this study.Methods: The medical records of pneumonia patients were gathered from the affiliated hospital of Qingdao University during Jan 1st, 2014, and Dec 31st,2018. Daily concentrations of PM2.5, PM10, SO2, NO2, as well as CO, were collected from the national air quality monitoring stations in Qingdao. A case-crossover study design and conditional logistic regression model were used to estimate the associations. Daily temperature, relative humidity, and atmospheric pressure were adjusted as the covariates in all models. A principal component analysis was used to solve the multicollinearity between atmospheric pollutants and investigate the relationship between various air pollutants and pneumonia occurs.Results: In the single pollutant model, with interquartile range increment of the density of PM2.5, PM10, SO2 and NO2 at the lag2 days, the odds ratio of hospital visits for pneumonia patients increased by 6.4% (95%CI, 2.3-10.7%), 7.7% (95%CI, 3.2-12.4%), 6.7% (95%CI, 1.0-12.7%), and 7.2% (95%CI, 1.1-13.5%). Stratified analysis showed that pollutants were more significant in the cold period. Besides, the impact of atmospheric particulates on different ages mainly occurs in the young child (0 to 3-year-old). The odds ratio was 1.042 (95%CI, 1.2-7.2%) when the principal components of atmospheric pollutants were included in the conditional logistic model.Conclusion: Our study found a significant relationship between short-term uncovering to PM2.5, PM10, NO2, SO2, and hospital visits for pneumonia in Qingdao. The effect of atmospheric pollutants mainly arose in a cold period. The particulate matter might be the principal reason in inducing hospital visits for pneumonia.

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Acute effects of air pollution on respiratory disease mortalities and outpatients in Southeastern China

Cited by 58 publications

References 33 publications

Association between ambient fine particulate matters and chronic obstructive pulmonary disease (COPD) mortality: an analysis in Southeastern China

Association between ambient fine particulate matters and chronic obstructive pulmonary disease (COPD) mortality: an analysis in Southeastern China

Air Pollutants and Hospital Visits for Pneumonia: A Case-crossover Study in Qingdao, China.

Ambient air pollutants and hospital visits for pneumonia: A case-crossover study in Qingdao, China.

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