Acute disseminated encephalomyelitis after renal transplantation in patients with positive Epstein-Barr virus antibody

Kim, S.-C; Jang, Hye-Won; Han, Duck Jong

doi:10.1016/s0041-1345(98)00967-1

Cited by 22 publications

(14 citation statements)

References 4 publications

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“…Sometimes the neurological condition may rapidly deteriorate to coma and death. [2] Neuroimaging is extremely important in establishing the diagnosis of ADEM. [1] MRI brain typically shows diffuse bilateral CNS demyelination with extensive involvement of white mater.…”

Section: Discussionmentioning

confidence: 99%

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Successful renal transplantation after recovery from acute disseminated encephalomyelitis in a child with end-stage renal disease

Bhosale¹,

Shah²,

Trivedi

2010

Indian Journal of Critical Care Medicine

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Acute disseminated encephalomyelitis (ADEM), seen mostly in children, is an acute demyelinating disease, affecting mainly the white matter of brain and spinal cord. We report an unusual case of ADEM in an 11-year old boy with endstage renal disease, who underwent hemopoietic stem cell transplantation prior to renal transplantation. He needed admission to the intensive care unit and required mechanical ventilation. He responded to intravenous injection of steroids and upon recovery, underwent renal transplantation successfully.

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Section: Discussionmentioning

confidence: 99%

“…There have been reports of ADEM after renal transplantation. [23] We report an unusual case of ADEM in a child suffering from end-stage renal disease who underwent hemopoietic stem cell transplantation (HSCT) prior to renal transplantation. Later the child underwent successful renal transplantation after recovery from ADEM.…”

Section: Introductionmentioning

confidence: 99%

Successful renal transplantation after recovery from acute disseminated encephalomyelitis in a child with end-stage renal disease

Bhosale¹,

Shah²,

Trivedi

2010

Indian Journal of Critical Care Medicine

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“…Although various viral and bacterial pathogens have been associated with ADEM, the preceding infection cannot be identified frequently (1,5,6), and ADEM after Epstein-Barr virus infection has only rarely been reported in English literature (7)(8)(9)(10)(11). In this report, we present a girl with ADEM associated with Epstein-Barr virus infection.…”

mentioning

confidence: 87%

“…She had clinical findings consistent with infectious mononucleosis and acute Epstein-Barr virus infection was confirmed by specific antibodies. Many uncommon and unusual conditions including aseptic meningitis, encephalitis, transverse myelitis, cranial nerve paralyses, ataxia, seizures, Alice in Wonderland syndrome, and Guillain-Barré syndrome have been reported to be associated with Epstein-Barr virus infection (7,12), however, ADEM has only rarely been reported (7)(8)(9)(10)(11).…”

mentioning

confidence: 99%

Acute Disseminated Encephalomyelitis Associated With Epstein-Barr Virus Infection

Çiftçi¹

2003

Journal of Ankara Medical School

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“…Although rare, ADEM may be seen in organ transplant patients on chronic immunosuppressive therapy [3]. The first case of ADEM after renal transplantation was reported in 1998 [4].…”

Section: Introductionmentioning

confidence: 99%

Fulminant acute disseminated encephalomyelitis in renal transplant patient treated by decompressive craniectomy: a case report

Spencer¹,

Vela‐Duarte²,

Sandrian³

et al. 2014

Neurosci Discov

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Background: Acute disseminated encephalomyelitis (ADEM) is a rare demyelinating disease of the central nervous system that most commonly afflicts children and young adults and may be rarely seen in renal transplant patients. Most cases resolve with medical management; however, in some instances, the initial episode may evolve into a fulminant illness with malignant cerebral edema and elevated intracranial pressure that can result in a herniation syndrome with possible fatal consequences. Immediate relief of intracranial pressure is a priority and medical therapies alone may not suffice or may be precluded by compromised renal function. Case description: A case is presented of fulminant ADEM in a pediatric renal transplant patient associated with intracranial hypertension and an acute herniation syndrome with rapid neurological decline that was effectively treated with a decompressive craniectomy. The procedure was life-saving and resulted in a favorable outcome without inflicting any additional morbidity. Conclusion: Decompressive craniectomy is an effective way to rapidly reduce intracranial pressure in patients with malignant cerebral edema associated with fulminant ADEM and rapid neurological decline.

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Acute disseminated encephalomyelitis after renal transplantation in patients with positive Epstein-Barr virus antibody

Cited by 22 publications

References 4 publications

Successful renal transplantation after recovery from acute disseminated encephalomyelitis in a child with end-stage renal disease

Successful renal transplantation after recovery from acute disseminated encephalomyelitis in a child with end-stage renal disease

Acute Disseminated Encephalomyelitis Associated With Epstein-Barr Virus Infection

Fulminant acute disseminated encephalomyelitis in renal transplant patient treated by decompressive craniectomy: a case report

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