Acute deafness as an extraintestinal manifestation of ulcerative colitis

Inner-ear obliteration in ulcerative colitis patients with sensorineural hearing loss

“…1 However, several reported sensorineural hearing loss cases, including ours, showed a poor response to steroid therapy. 3,18,19 Cochlear fibrosis or osteoneogenesis may ensue following autoimmune labyrinthitis. In our patients, we found that the inner ears with MRI evidence of obliteration (i.e.…”

“…2 Subsequently, sensorineural hearing loss was recognised as one of the extra-intestinal manifestations of ulcerative colitis. 3 Three-dimensional, T2-weighted magnetic resonance imaging (MRI) is an excellent imaging modality with which to visualise the soft tissue structures of the inner ear. 4 However, no previous report has described the innerear findings seen on three-dimensional MRI in ulcerative colitis patients presenting with sensorineural hearing loss.…”

Symptomatic sensorineural hearing loss in patients with ulcerative colitis

“…Most data on this association have been reported as single case reports [7][8][9][10][11], and few studies that investigated patient series [12][13][14] suggested that pauci-or asymptomatic SNHL may be found in up to about 40 % of UC patients. Since the clinical course of hearing loss is independent from that of UC, and if the disorder is not recognized, it causes permanent hearing loss, and it has been suggested that it is important to identify SNHL in its early phases [12].…”

“…The latter may include sensorineural hearing loss (SNHL) [4], i.e., sudden or progressive hearing impairment due to the degeneration of various components of the cochlea [5], which was first associated with IBD by Levitan in 1973 [6]. Since then, SNHL in UC has been mainly described as single case reports [7][8][9][10][11], and the few studies conducted on series of patients with IBD have demonstrated that this condition is more prevalent (although often with subclinical manifestations) in adult UC patients [12][13][14], whereas it has not been found in pediatric IBD series [15].…”

Ulcerative Colitis Associated with Isolated Unilateral Hypoglossal Nerve Palsy

“…Recent studies have focused on probable manifestations of UC in the nervous system, although few have noted neuropathy, and other EIMs have been reported (1-4). To the best of our knowledge, there are no reports of neuropathy of the hypoglossal nerve occurring in association with UC, although some studies have that noted the occurrence of cranial nerve disorders, such as optic neuritis, and sensorineural hearing loss (1,(5)(6)(7)(8)(9)(10)(11). Furthermore, one study found that demyelinating diseases occur more frequently in patients with UC than in non-UC patients (12).…”