The development of medical domain applications has been one of the most active research areas recently. One example of a medical domain application is a detection system for heart disease based on computer-aided diagnosis methods, where the data is obtained from some other sources and is evaluated by computer based applications. Up to now, computers have usually been used to build knowledge based clinical decision support systems which used the knowledge from medical experts, and transferring this knowledge into computer algorithms was done manually. This process is time consuming and really depends on the medical expert's opinion, which may be subjective. To handle this problem, machine learning techniques have been developed to gain knowledge automatically from examples or raw data. Here, a weighted fuzzy rule-based clinical decision support system (CDSS) is presented for the diagnosis of heart disease, automatically obtaining the knowledge from the patient's clinical data. The proposed clinical decision support system for risk prediction of heart patients consists of two phases, (1) automated approach for generation of weighted fuzzy rules and decision tree rules, and, (2) developing a fuzzy rule-based decision support system. In the first phase, we have used the mining technique, attribute selection and attribute weightage method to obtain the weighted fuzzy rules. Then, the fuzzy system is constructed in accordance with the weighted fuzzy rules and chosen attributes. Finally, the experimentation is carried out on the proposed system using the datasets obtained from the UCI repository and the performance of the system is compared with the neural network-based system utilizing accuracy, sensitivity and specificity.
The use of data mining approaches in medicine and medical science has become necessary especially with the evolution of these approaches and their contributions medical decision support. Coronary artery disease (CAD) touches millions of people all over the world including a major portion in Algeria. However, much advancement has been done in medical science, but the early detection of CAD is still a challenge for prevention. Although, the early detection of CAD is a prevention challenge for clinicians. The subject of this paper is to propose new clinical decision support system (CDSS) for evaluating risk of CAD called CADSS. In this paper, the authors describe the characteristics of clinical decision support systems CDSSs for the diagnosis of CAD. The aim of this study is to explain the clinical contribution of CDSSs for medical decision-making and compare data mining techniques used for their implementation. Then, they describe their new fuzzy logic-based approach for detecting CAD at an early stage. Rules were extracted using a data mining technique and validated by experts, and the fuzzy expert system was used to handle the uncertainty present in the medical field. This work presents the main risk factors responsible for CAD and presents the designed CASS. The developed CADSS leads to 94.05% of accuracy, and its effectiveness was compared with different CDSS.
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