Acute cerebellitis with hydrocephalus

Doğulu, Fikret; Önk, Ayhan; Kaymaz, Memduh; Kardeş, Özgür; Mk, Baykaner

doi:10.1212/01.wnl.0000064168.64413.ff

Cited by 10 publications

(2 citation statements)

References 2 publications

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“…C-shaped cerebellar white matter T2 hyperintensity demonstrated in post-infectious cerebellitis is caused by cerebellar white matter vasogenic edema [6]. Resolution of the hyperintense areas in the cerebellar cortex can be associated with recovery from the clinical manifestations, although mild cerebellar atrophy may be seen in follow up MRI scans [7]. …”

Section: Discussionmentioning

confidence: 99%

Epstein-Barr virus co-infection in a patient with dengue fever presenting with post-infectious cerebellitis: a case report

2012

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IntroductionPost-infectious cerebellitis is an acute form of inflammatory encephalitis mainly limited to the cerebellum. It is commonly found in children, especially after viral infections such as Epstein-Barr virus. Post-infectious cerebellitis presents with acute onset dysarthria and ataxia. To the best of our knowledge, this is the first case report of post-infectious cerebellitis in a patient with both dengue and Epstein-Barr viral infection confirmed on serology.Case presentationA 43-year-old Sri Lankan Sinhala man presented with an acute febrile illness associated with thrombocytopenia. While being managed as uncomplicated dengue fever, our patient developed dysarthria, ataxia and cerebellar signs. Our patient's infectious disease screen was positive for both dengue and Epstein-Barr specific immunoglobulin M. A cerebrospinal fluid analysis was suggestive of viral meningoencephalitis while cerebrospinal fluid serology was positive for dengue immunoglobulin G. T2-weighted magnetic resonance images were consistent with post-viral cerebellitis. The patient was given full supportive care and he made an uneventful complete recovery.ConclusionThere have been no previously reported cases of post-infectious cerebellitis associated with both Epstein-Barr and dengue viral infections confirmed by serology. Our patient's clinical features and findings on the imaging studies were consistent with post-viral cerebellitis. This report highlights the need to screen for other possible more common etiologies of a particular presentation before coming to a specific diagnosis based on initial findings. Uncomplicated cases of cerebellitis can be successfully managed with appropriate supportive measures with good prognosis, as in this case.

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Section: Discussionmentioning

confidence: 99%

Epstein-Barr virus co-infection in a patient with dengue fever presenting with post-infectious cerebellitis: a case report

2012

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“…Abnormal MRI enhancement may be seen in some but not all cases in acute and subacute stages of the disease In general the characteristic MRI T2 and FLAIR picture of postinfectious cerebellitis is bilateral, symmetrical hyperintensities involving the cerebellar white matter and taking exactly the shape of the cerebellar white matter and mapping it (C-shaped hyperintensity). The C-shape hyperintensity is due to cerebellar white matter vasogenic edema that develops secondary to the immune mediated inflammatory demyelination of the white matter of the cerebellum which results in breakdown of the blood brain barrier with subsequent development of vasogenic edema that follows the myelinated axons of white matter tracts and association fibers of the cerebellum, spreading them apart and extending alongside them resulting in the characteristic C-shape of the [6][7][8] MRI T2 and FLAIR hyperintensities.…”

Section: Discussionmentioning

confidence: 99%

Acute Post Infectious Cerebellitis Presenting as Hydrocephalus: A Rare Presentation

Asmi¹,

Masoodi²,

Imran³

et al. 2010

JMS

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Acute post infectious cerebellitis, also known as acute cerebellar ataxia, is a rare inflammatory syndrome often characterized by cerebellar dysfunction of rapid onset. Although usually benign and self-limiting, acute cerebellitis may manifest a fulminant course. We describe a patient referred to our center with acute cerebellitis, complicated by hydrocephalus. An 32-year-old female presented with headache, nausea, vomiting, and gait and limbs ataxia 2 weeks after following a respiratory tract infection. CT showed obstructive hydrocephalus. MRI showed bilateral cerebellar swelling with hyperintense signals on T2-weighted imaging. The diagnosis was acute post infectious cerebellitis. Following treatment with corticosteroids, the clinical signs resolved. The patient made an uneventful recovery, with elimination of neurologic deficit.(JMS 2010;13(2):67-69)

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Magnetic resonance imaging findings in patients presenting with (sub)acute cerebellar ataxia

et al. 2015

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Acute cerebellitis with hydrocephalus

Cited by 10 publications

References 2 publications

Epstein-Barr virus co-infection in a patient with dengue fever presenting with post-infectious cerebellitis: a case report

Epstein-Barr virus co-infection in a patient with dengue fever presenting with post-infectious cerebellitis: a case report

Acute Post Infectious Cerebellitis Presenting as Hydrocephalus: A Rare Presentation

Magnetic resonance imaging findings in patients presenting with (sub)acute cerebellar ataxia

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