Acute bilateral facial palsy and Wegener's disease

Magliulo, Giuseppe; Parrotto, Donato; Alla, François; Gagliardi, Silvia

doi:10.1016/j.otohns.2008.04.010

Cited by 10 publications

(12 citation statements)

References 5 publications

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“…In 2001, Nikolaou et al reported 22 cases of facial nerve paralysis in the course of WG [16]. At present, it is estimated that the facial nerve palsy occurs in 5% to 8% of the WG patients [8, 11, 17]. However, the bilateral facial nerve paralysis is described extremely rarely in the literature [8, 16, 17].…”

Section: Discussionmentioning

confidence: 99%

“…At present, it is estimated that the facial nerve palsy occurs in 5% to 8% of the WG patients [8, 11, 17]. However, the bilateral facial nerve paralysis is described extremely rarely in the literature [8, 16, 17]. Preuss et al presented a case of the bilateral facial nerve palsy, in the course of WG, with the lungs and kidneys involvement, which has been fatal due to multiple organ failure in spite of intensive treatment [18].…”

Section: Discussionmentioning

confidence: 99%

“…Described in the current literature cases of the facial nerve paralysis in a course of WG, treated surgically, shows that surgical treatment does not improve the prognosis, but could increase the risk of further facial nerve damage [10, 11, 15, 17]. However Magliulo et al and Gottschlich et al emphasized in their publications that in case of purulent otorrhea, not responding to antibiotics, or in case of symptoms of mastoiditis, the surgical treatment should be implemented [5, 17]. In our case, we observed rapid improvement of hearing, pain relief, and functional facial nerve recovery on the operated side, comparing to the opposite ear, suggesting the reasonability of surgical treatment.…”

Section: Discussionmentioning

confidence: 99%

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Bilateral Facial Palsy in Rapidly Progressive Course of Wegener’s Granulomatosis: A Case Report

Roszkowska

Morawska-Kochman

Temporale

et al. 2013

Case Reports in Otolaryngology

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Introduction. Wegener's granulomatosis belongs to a group of systemic vasculitis diseases, which is characterized by necrotizing vasculitis and presence of granulomas. In a lot of cases, the first symptoms of the disease are observed in the head and neck region, but the bilateral facial nerve palsy occurs very rarely. Objective. The objective of our report was to describe the unusual course of Wegener's granulomatosis with the bilateral facial nerve paralysis, which subsided after application of steroids and immunosuppressive therapy in combination with surgical treatment. Results and Conclusions. Hearing loss may precede other symptoms in Wegener's granulomatosis. Ear pain and otorrhea may suggest the diagnosis of bacterial purulent otitis media and delay the proper diagnosis. In the presented case, considering the clinical course, it was necessary to apply both pharmacological and surgical treatments.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Bilateral Facial Palsy in Rapidly Progressive Course of Wegener’s Granulomatosis: A Case Report

Roszkowska

Morawska-Kochman

Temporale

et al. 2013

Case Reports in Otolaryngology

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“…These manifestations are caused by the granulomatous process in the temporal bone and nasopharynx [10]. The incidence of otologic involvement varies from 19% to 61% in recent literature [1,3,6,11]. Facial palsy is a rare manifestation of WG (5%) and is far less common as the primary presenting symptom [7].…”

Section: Introductionmentioning

confidence: 99%

Wegener's Granulomatosis Presenting with Bilateral Facial Nerve Palsy and Limited to the Head and Neck

Macdonald¹,

Maria²

2013

Journal of Case Reports in Medicine

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Objectives. To illustrate the only reported case of Wegener's granulomatosis limited to the head and neck, and to provide an update on current knowledge and treatment of Wegener's granulomatosis. Case report. A 50-year-old man presented with bilateral chronic otitis and mastoiditis, eventually developing bilateral facial palsies. While he progressed with other head and neck symptoms, his disease was limited entirely to the head and neck. Diagnosis of Wegener's granulomatosis was delayed for this reason, due to the lack of systemic manifestations and the inability to confirm the diagnosis with a tissue biopsy, despite an elevated c-ANCA level. Conclusion. The early diagnosis and initiation of appropriate treatment of Wegener's granulomatosis is essential to prevent progression of the disease to a severe and irreversible phase. This case emphasizes that an awareness of this rare presentation is important to prevent the unnecessary delay of appropriate treatment in order to optimize the patient's prognosis, particularly when classic therapy for otitis or facial palsy is ineffective.

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“…A case report is presented of a 35-year-old male with sequential bilateral otitis media, progressive mixed hearing loss, tinnitus, otalgia, otorrhea, and, later, bilateral facial nerve paralysis. A review of the literature demonstrates only six cases of bilateral facial palsy from WG worldwide, with this case representing the first in the United States [1,2,4,6,7,8].…”

Section: Introductionmentioning

confidence: 99%

Sequential Bilateral Otitis Media and Bilateral Facial Nerve Paralysis as Presenting Symptoms of Wegener's Granulomatosis

Cerrati

Hartman²,

Gottlieb³

et al. 2013

Journal of Case Reports in Medicine

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Wegener's granulomatosis is an incurable vasculitis that can be life-threatening when end-organ damage occurs. Symptoms most commonly affect the nose, lungs, and kidneys. We present a case study of a 35-year-old male who presented with sequential bilateral otitis media, progressive mixed hearing loss, tinnitus, otalgia, otorrhea, and, later, bilateral facial nerve paralysis despite aggressive antibiotic intervention. The accompanying review of the literature demonstrates only six other patients worldwide with these presenting symptoms. Treatment options and outcome will be discussed.

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Acute bilateral facial palsy and Wegener's disease

Abstract: [No abstract available

Cited by 10 publications

References 5 publications

Bilateral Facial Palsy in Rapidly Progressive Course of Wegener’s Granulomatosis: A Case Report

Bilateral Facial Palsy in Rapidly Progressive Course of Wegener’s Granulomatosis: A Case Report

Wegener's Granulomatosis Presenting with Bilateral Facial Nerve Palsy and Limited to the Head and Neck

Sequential Bilateral Otitis Media and Bilateral Facial Nerve Paralysis as Presenting Symptoms of Wegener's Granulomatosis

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