Acute bacterial prostatitis after transrectal prostate needle biopsy: clinical analysis

Shigehara, Kazuyoshi; Miyagi, Tohru; Nakashima, Tsutomu; Shimamura, Masayoshi

doi:10.1007/s10156-007-0570-3

Cited by 74 publications

(66 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…All patients were treated with C3G or carbapenem with similar results in both groups. 17 Another important issue should be discussed. Some of the biopsyrelated infectious complications can be avoided when a transperineal approach is taken.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Acute bacterial prostatitis after transrectal ultrasound‐guided prostate biopsy: Epidemiological, bacteria and treatment patterns from a 4‐year prospective study

et al. 2013

View full text Add to dashboard Cite

Abbreviations & AcronymsObjectives: To evaluate the incidence, and clinical and bacterial features of iatrogenic prostatitis within 1 month after transrectal ultrasound-guided biopsy for detection of prostate cancer. Methods: From January 2006 to December 2009, 3000 patients underwent a 21-core transrectal ultrasound-guided prostate biopsy at Henri Mondor Hospital (Créteil, France) and were prospectively followed. All patients had a fluoroquinolone antimicrobial prophylaxis for 7 days. The primary study end-point was to evaluate the incidence of iatrogenic acute prostatitis within 1 month after the biopsy. The secondary end-point was to analyze the clinical and the bacterial features of the prostatitis. Results: Overall, 20 patients of the entire study population (0.67%) had an acute bacterial prostatitis within 2.90 ± 1.77 days (range 1-7 days) after the transrectal ultrasound-guided biopsy. The groups of patients with (n = 20) and without (n = 2980) infection were similar in terms of age, prostate-specific antigen level and prostate volume. Escherichia coli was the only isolated bacteria. The subsequent tests for antibiotic susceptibility showed a 95% resistance for fluroquinolone and amoxicillin. Resistance to amoxiclav, trimethoprimsulfamethoxazole, third generation cephalosporin and amikacin was 70%, 70%, 25% and 5% respectively. No resistance to imipenem was reported. They were all admitted for treatment without the need of intensive care unit referral. Complete recovery was achieved after 21.4 ± 7 days of antibiotic treatment. Conclusions: A fluroquinolone-based regimen still represents an appropriate prophylaxis protocol to minimize the risk of acute prostatitis secondary to prostate biopsy. Patients should be provided the appropriate care soon after the onset of the symptoms. An intravenous third generation cephalosporin or imipenem-based therapy seem to provide satisfying results.

show abstract

Section: Discussionmentioning

confidence: 99%

“…The long regimen is now only considered for high-risk patients due to competitive comorbidities, as supported by some authors in the literature. 3,17,18 This might include: chronic respiratory disease, recent hospitalization, a recent use of antibiotics and overseas travel. We are aware of the poor evidence of this approach.…”

Section: Discussionmentioning

confidence: 99%

Acute bacterial prostatitis after transrectal ultrasound‐guided prostate biopsy: Epidemiological, bacteria and treatment patterns from a 4‐year prospective study

et al. 2013

View full text Add to dashboard Cite

show abstract

“…16 Although none of our patients developed any major complications from their post-biopsy infections, such complications have been reported and may be serious. New antibiotic regimens should be developed for TRUS-guided prostate biopsies.…”

Section: Discussionmentioning

confidence: 61%

Effect of needle size on cancer detection, pain, bleeding and infection in TRUS-guided prostate biopsies: a prospective trial

McCormack

Duclos

Latour

et al. 2012

CUAJ

View full text Add to dashboard Cite

Introduction: Transrectal ultrasound (TRUS)-guided prostate biopsies using 18G calibre needles are widely used; most often 12-core tissue samples of the peripheral zone are obtained. Although the diagnostic yield of prostate biopsies is fair, there is still a potential for false negative results, which necessitates repeat biopsies. In an effort to improve the accuracy of prostate biopsies, different sampling schemes have been developed. One strategy has been to increase the number of core biopsies performed on each patient. Another strategy has been to improve the reliability of prostate biopsies using larger calibre needles, thereby increasing the amount of tissue obtained for each core biopsy. Methods: After approval by our institutional review board, we prospectively compared two biopsy needle sizes (18G vs. 16G) in relation to prostate cancer diagnosis, pain, bleeding and infection rates on 105 patients. Each patient underwent 6 TRUS-guided prostate biopsies with the standard 18G needle and 6 other biopsies with the experimental 16G needle. To evaluate possible complications related to the use of a larger 16G needle in the experimental group, we compared pain, bleeding and infection rates with a control group of 100 patients who underwent 12 biopsies with a single 18G needle (18G group). Pain, bleeding assessment and infection events were evaluated using patient questionnaires and telephone interviews. Results: TRUS-guided prostate biopsies using 16G calibre needles did not increase cancer detection or non-malignant pathology rate, including prostatic intraepithelial neoplasia (PIN) and atypical small acinar proliferatio (ASAP). Pain, bleeding and infectious complications were similar in both groups. Infection was defined as temperature above 38°C occurring within 48 hours after the procedure. We identified 4 patients with post-biopsy fever in the experimental (16/18G) group and 4 other patients in the (18G) control group. The post-biopsy infection rate is higher than reported just a few years ago and indicates that quinolone resistant Escherichia coli seems to be more prevalent in our urban setting than previously suspected. Limitations to our study include small group numbers. Conclusion: Larger 16G needles appear to be safe for TRUS-guided prostate biopsies. Further study in a larger, multi-institutional, prospective, randomized manner with 16G needles is warranted to assess the theoretical benefit of larger core biopsies in prostate cancer detection.

show abstract

“…[6,[17][18][19][20][21] Ciprofloxacin-resistant pathogens and nosocomial acquisition or prior instrumentation have been associated with increased antibiotic resistance and higher clinical failure rates. [22] In our study, pathogens isolated in urine cultures were observed to be resistant to fluoroquinolones in 81.1% of the patients.…”

Section: Discussionmentioning

confidence: 99%

“…The diagnosis of ABP was established upon fever higher than 38°C, >5-10 white blood cells/high power field leukocytes in urine sediments, and positive urine and/or positive blood cultures. [6] Standard blood biochemistry tests, semi-quantitative urine dip stick tests, and urine cultures for microbiological examinations were performed for all patients.…”

Section: Methodsmentioning

confidence: 99%

Prostate Biopsy Related Acute Bacterial Prostatitis: Current Microbiological Spectrum, Sensitivity to Antibiotics And Clinical Findings In Turkey

Türk

Ün

Şener

et al. 2018

EJMO

View full text Add to dashboard Cite

Acute bacterial prostatitis after transrectal prostate needle biopsy: clinical analysis

Cited by 74 publications

References 24 publications

Acute bacterial prostatitis after transrectal ultrasound‐guided prostate biopsy: Epidemiological, bacteria and treatment patterns from a 4‐year prospective study

Acute bacterial prostatitis after transrectal ultrasound‐guided prostate biopsy: Epidemiological, bacteria and treatment patterns from a 4‐year prospective study

Effect of needle size on cancer detection, pain, bleeding and infection in TRUS-guided prostate biopsies: a prospective trial

Prostate Biopsy Related Acute Bacterial Prostatitis: Current Microbiological Spectrum, Sensitivity to Antibiotics And Clinical Findings In Turkey

Contact Info

Product

Resources

About