Acute Bacterial Meningitis

Mace, Sharon E.

doi:10.1016/j.emc.2008.02.002

Cited by 87 publications

(117 citation statements)

References 76 publications

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“…Meningite bacteriana causada por S. pneumoniae foi selecionada como fator de risco para o desenvolvimento de complicações neurológicas agudas [razão de chances (odds ratio, OR) = 6,4; intervalo de confiança (IC) 1,[7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24]7], assim como neutropenia < 60% (p < 0,01). …”

Section: Métodosunclassified

“…As meningites bacterianas agudas (MBA) caracterizam-se por ser um processo infeccioso que acomete as leptomeninges e o espaço subaracnóideo 1 . Apesar dos cuidados intensivos e avanços na terapêutica, ainda são responsáveis por uma elevada taxa de morbimortalidade [2][3][4] , estando entre as 10 maiores causas de mortalidade por doenças infecciosas no mundo, principalmente na população pediátrica 5 .…”

Section: Introductionunclassified

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Childhood acute bacterial meningitis: risk factors for acute neurological complications and neurological sequelae

Antoniuk¹,

Hamdar²,

Ducci³

et al. 2011

J Pediatr (Rio J)

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Objective: To assess acute neurological complications and neurological sequelae of childhood acute bacterial meningitis in order to determine possible warning signs. Methods:This retrospective study evaluated children with acute bacterial meningitis (between 1 month and 14 years of age) admitted between 2003 and 2006. Results:Of the 44 patients studied, 17 (38.6%) had acute neurological complications. Seizure was the most frequent (31.8%) complication. Patients with acute neurological complications showed a higher frequency of lower neutrophil count (p = 0.03), seizure at admission (p < 0.01), and S. pneumoniae as the etiologic agent (p = 0.01). Risk factors for the development of acute neurological complications were S. pneumoniae (odds ratio [OR] = 6.4, confidence interval [CI] 1.7-24.7) and neutrophil count < 60% (p < 0.01). Of the 35 patients who were followed up, 14 had neurological sequelae (40%). Behavioral change (22.9%) was the most frequent sequela. Seizures at admission (OR = 5.6, CI 1.2-25.9), cerebrospinal fluid protein concentration > 200 mg/dL (p < 0.01), and cerebrospinal fluid glucose concentration/glycemia ratio (p < 0.01) were identified as risk variables for sequelae. Conclusion:Neutrophil count < 60%, seizure at admission, and S. pneumoniae as the etiologic agent were identified as warning signs for acute neurological complications, while protein levels, cerebrospinal fluid glucose concentration/glycemia ratio, and seizure at admission were seen as risk factors for neurological sequelae.J Pediatr (Rio J). 2011;87(6):535-40: Bacterial meningitis, neurological complications, neurological follow-up, pediatrics. ResumoObjetivo: Estudo retrospectivo que visa avaliar as complicações neurológicas agudas e sequelas neurológicas das meningites bacterianas agudas na infância, a fim de determinar possíveis sinais de alerta. Conclusão: Contagem de neutrófilos < 60%, crise convulsiva na admissão e S. pneumoniae como agente etiológico foram identificados como sinais de alerta para a ocorrência de complicação neurológica aguda, enquanto que proteinorraquia, menor relação glicorraquia/glicemia e crise convulsiva na internação foram observados como fatores de risco para a ocorrência de sequelas neurológicas.J Pediatr (Rio J). 2011;87(6):535-40

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Section: Métodosunclassified

Section: Introductionunclassified

Childhood acute bacterial meningitis: risk factors for acute neurological complications and neurological sequelae

Antoniuk¹,

Hamdar²,

Ducci³

et al. 2011

J Pediatr (Rio J)

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“…While Haemophilus influenzae was previously the most frequent cause of acute bacterial meningitis in the United States, widespread vaccination against this pathogen has resulted in Streptococcus pneumoniae supplanting H. influenzae as the leading cause of bacterial meningitis. 1 Vaccination against S. pneumoniae is now reducing the incidence of central nervous system infections caused by this bacterium. 2 As the burden of pneumococcal meningitis wanes, a relative increase in the proportion of cases caused by other streptococci emerges.…”

Section: Clinical and Laboratory Features Of Streptococcus Salivariusmentioning

confidence: 99%

Clinical and Laboratory Features of Streptococcus salivarius Meningitis: A Case Report and Literature Review

Wilson¹,

Ryan²,

Walk³

et al. 2011

Clinical Medicine & Research

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Streptococcus salivarius is a normal member of the human oral microbiome that is an uncommon cause of invasive infections. Meningitis is a rare but increasingly reported infection caused by S. salivarius. Despite the growing number of reported cases, a comprehensive review of the literature on S. salivarius meningitis is lacking. We sought to gain a better understanding of the clinical presentation, evaluation, management, and outcome of S. salivarius meningitis by analyzing previously reported cases. In addition to a single case reported here, 64 previously published cases of meningitis were identified for this review. The collected data confirm that most patients presented with classical signs and symptoms of bacterial meningitis with a predominance of neutrophils in the cerebrospinal fluid (CSF) and hypoglycorrhachia. The majority of cases followed iatrogenic or traumatic CSF contamination. Most cases were diagnosed by CSF culture within one day of symptom onset. There was no clear evidence of predisposing co-morbid conditions in patients with meningitis, although in most case reports, limited information was given on the medical history of each patient. Outcomes were generally favorable with antibiotic management. Clinicians should suspect S. salivarius meningitis in patients presenting acutely after medical or surgical procedures involving the meninges.

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“…The inflammation and swelling may extend through the membranes of the pia mater, arachnoid or subarachnoid (Mace, 2008). Meningitis can be classified into infectious and noninfectious disease.…”

Section: Introductionmentioning

confidence: 99%

“…Infectious meningitis can be further sub-divided to non-bacterial and bacterial (pyogenic) meningitis. Non-bacterial meningitis is typically caused by viral or fungal infections (Mace, 2008). Bacterial meningitis is characterized by the significant polymorph nuclear changes in the cerebrospinal fluid (CSF).…”

Section: Introductionmentioning

confidence: 99%

Bacterial meningitis: An update review

Bekairy¹,

Harbi²,

Alkatheri³

et al. 2014

Afr. J. Pharm. Pharmacol.

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Bacterial meningitis is still considered serious life-threatening disease in spite of the decline in the morbidity and mortality in the last decade. The expeditious diagnosis of the disease, a prompt empiric antibiotic treatment and the proper adjunctive therapy are corner stones for the successful management of the disease. The objective of this review is to provide the health care professionals with an update of reference for bacterial meningitis diagnosis and treatment. In addition, the various types of vaccines and the empiric chemoprophylaxis treatment are reviewed.

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Acute Bacterial Meningitis

Cited by 87 publications

References 76 publications

Childhood acute bacterial meningitis: risk factors for acute neurological complications and neurological sequelae

Childhood acute bacterial meningitis: risk factors for acute neurological complications and neurological sequelae

Clinical and Laboratory Features of Streptococcus salivarius Meningitis: A Case Report and Literature Review

Bacterial meningitis: An update review

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