Acute autonomic neuropathy. Two cases and a clinical review

Hart, Robert G.; Kanter, Merrill C.

doi:10.1001/archinte.150.11.2373

Cited by 22 publications

(22 citation statements)

References 37 publications

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“…The latter is featured with orthostatic hypotension and positive Lying-Standing test, and it has been found in 4 patients who also presented cholinergic [14]. Some literatures have pointed that acute cholinergic dysfunction particularly affected younger people [15]. According to the literature, some patients exhibited somatic motor or sensory dysfunction [16].…”

Section: Discussionmentioning

confidence: 99%

Acute autonomic neuropathy with severe gastrointestinal symptoms in children: a case series

et al. 2017

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Background: Acute autonomic neuropathy (AAN) is rare disorder with anecdotal report, especially for childhood onset patients. Misdiagnosis or delays in treatment can always be found in clinical practice. We conducted this study to give a description of the manifestations and treatment of AAN in children and therefore help clinicians to make the accurate diagnosis early so that the prognosis of the patients can be improved.

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Section: Discussionmentioning

confidence: 99%

Acute autonomic neuropathy with severe gastrointestinal symptoms in children: a case series

et al. 2017

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“…This disorder is characterized by subacute onset and monophasic course with partial recovery. There is sympathetic, parasympathetic and enteric failure with no significant evidence of somatic peripheral neuropathy [8,28]. Specific antibodies directed against the neuronal ganglionic AChR in autonomic ganglia have been found in about 50% of patients with this disorder [36].…”

Section: Autoimmune Autonomic Ganglionopathymentioning

confidence: 99%

“…A presumed antecedent viral infection may be reported in about 60% of cases [28]. The spinal fluid protein is often elevated [8,28].…”

Section: Autoimmune Autonomic Ganglionopathymentioning

confidence: 99%

Antibody testing as a diagnostic tool in autonomic disorders

Vernino

2008

Clin Auton Res

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Some forms of peripheral autonomic dysfunction (especially enteric neuropathy and subacute panautonomic failure) occur as autoimmune phenomena either in isolation or in the context of cancer. Autoimmune autonomic ganglionopathy is an example of a severe, but potentially treatable, antibody-mediated form of autonomic failure. Diagnostic evaluation of autonomic disorders can be supplemented by testing for paraneoplastic antibodies and antibodies against membrane receptors. The diagnostic antibodies most commonly associated with dysautonomia are paraneoplastic antibodies (anti-Hu and CRMP-5) and ganglionic acetylcholine receptor antibodies.

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“…The concomitant manifestation of sensory and motor impairment has been reported in patients with autonomic neuropathy with a monophasic clinical course similar to Guillain-Barré syndrome (GBS) (1)(2)(3)(4)(5)(6). Some of these patients were reported to have acute autonomic sensory and motor neuropathy (AASMN) (3)(4)(5)(6).…”

Section: Introductionmentioning

confidence: 99%

Differential Recovery in Cardiac and Vasomotor Sympathetic Functional Markers in a Patient with Acute Autonomic Sensory and Motor Neuropathy

et al. 2013

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Acute autonomic sensory and motor neuropathy (AASMN) is characterized by prominent dysautonomia with somatic sensory and motor impartment. Prominent dysautonomia is observed during the early phase of AASMN. We herein describe a case of AASMN that involved prolonged autonomic failure and disturbance of sensation despite a rapid recovery from motor weakness. The early and delayed heart-to-mediastinum ratios on 123 I-meta-iodobenzylguanidine myocardial scintigraphy were decreased and improved within seven months. However, orthostatic hypotension was prolonged. These results suggest a differential improvement in the cardiac and vasomotor sympathetic functions.

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Acute autonomic neuropathy. Two cases and a clinical review

Cited by 22 publications

References 37 publications

Acute autonomic neuropathy with severe gastrointestinal symptoms in children: a case series

Acute autonomic neuropathy with severe gastrointestinal symptoms in children: a case series

Antibody testing as a diagnostic tool in autonomic disorders

Differential Recovery in Cardiac and Vasomotor Sympathetic Functional Markers in a Patient with Acute Autonomic Sensory and Motor Neuropathy

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