Acute Aseptic Meningitis as the Only Presenting Feature of Leptospirosis

Karande, Sunil; Patil, Shailesh; Kulkarni, Madhuri; Joshi, Anagha; Bharadwaj, Renu

doi:10.1097/01.inf.0000157351.44089.7e

Cited by 15 publications

(14 citation statements)

References 4 publications

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“…In its classical form of systemic leptospirosis (Weil's disease), involvement of CNS [7] presenting as encephalitis [8], meningitis [9], primary meningitis [10], cerebral venous thrombosis [11], and cerebellitis [12] is well documented. Meningitis can be a significant feature of the clinical profile of leptospirosis, principally in the milder, anicteric forms of the disease.…”

Section: Discussionmentioning

confidence: 99%

Acute encephalitis as initial presentation of leptospirosis

Puca¹,

Majko²,

Puca

et al. 2017

J Infect Dev Ctries

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Encephalitis is an acute inflammation of the brain matter, very often associated with viral infections, but it can also be caused by non-viral pathogens such as leptospirosis. Leptospirosis is a systemic disease caused by bacteria of the Leptospira genus. Leptospiral infection has a broad spectrum of clinical manifestations ranging from subclinical or mild illness to a fulminant life-threatening illness. In this case report we describe a young patient from Southern Albania with isolated encephalitis caused by Leptospira, where acute encephalitis was the initial presentation of the disease.

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Section: Discussionmentioning

confidence: 99%

Acute encephalitis as initial presentation of leptospirosis

Puca¹,

Majko²,

Puca

et al. 2017

J Infect Dev Ctries

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“…Neurological manifestations are frequent in leptospirosis, especially aseptic meningitis [2]. Other syndromes described include cerobrovascular accidents [5][6], polyneuropathies [7], transverse myelitis [3], Guillan-Barré syndrome [4], mononeuritis multiplex [8][9] and cranial nerve palsies [10][11][12].…”

Section: Discussionmentioning

confidence: 99%

“…Leptospirosis is an acute feverish disease with a broad clinical spectrum and a characteristic biphasic course (leptospiremia and immune phases). Numerous neurological manifestations have been described during the immune phase [2][3][4][5][6][7][8][9][10][11][12].…”

mentioning

confidence: 99%

Bilateral facial palsy associated with leptospirosis

Silva¹,

Ducroquet²,

Pedrozo³

2009

Braz J Infect Dis

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Leptospirosis is a zoonosis of worldwide occurrence caused by the spirochete Leptospira interrogans. It is an acute feverish disease with a broad clinical spectrum and follows a characteristic biphasic course. Bilateral facial palsy is a rare clinical condition and the differential diagnosis of its causes is extensive. The objective of this exploratory study, presented as a case report, is to describe the occurrence of bilateral facial palsy as an unusual manifestation of leptospirosis. This suggestion should not be overlooked when analyzing the causes for bilateral facial palsy, and should be considered with other possible differential diagnoses, some of which are potentially fatal.

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“…[1,2,9] Symptomatic infection presents as a sudden-onset febrile illness with nonspeciÞ c signs and symptoms (70%) or as aseptic meningitis (20%) or hepatorenal dysfunction (10%). [1,2,36] Both anicteric (90% or more cases) and icteric leptospirosis are known to occur. [1][2][3][4][5][6]8] The more common, mild, anicteric form of the disease is characterized by nonspeciÞ c symptoms such as fever, headache, chills, myalgia, nausea, and abdominal pain, while the severe, potentially fatal, icteric form of leptospirosis (Weil's syndrome) is characterized by renal, hepatic, and vascular complications.…”

Section: Clinical Featuresmentioning

confidence: 99%