. METHODOLOGY: A retrospective analysis of histopathology reports of 1468 appendix specimen of patients of all age and gender who underwent appendectomy for acute appendicitis was done. Enterobius vermicularis was found to be most common worm present in the appendix followed by ascaris species. Detail histopathology reports of 76 cases with appendiceal enterobius vermicularis infestation were examined. Data were analyzed through IBM SPSS version 20. RESULTS: A total of 76 specimens of appendiceal enterobius vermicularis infestation among 1468 appendectomy cases produce a frequency of 5.17%. Mean age group of patients with appendiceal enterobius vermiculars infestation was 14.38±9.83 year with an overwhelming (50.76%) presenting in second decade of life. Male to female ratio was 1.24:1.Normal histology (n=48, 63.15%) was most frequently reported followed by lymphoid hyperplasia (n=18, 25%), whereas only 08(10.52%) cases of enterobius vermicular infestation had acute supportive appendicitis. CONCLUSIONS: Entrobius vermicular is the most common worm infestation in appendix and result in symptoms mimicking acute appendicitis without causing acute inflammation of the appendix. So it cannot be considered conclusively in the etiology of acute appendicitis. Antihelminthic therapy must be instituted for cases of entesobuis vermicular is infestation. KEYWORDS: Acute appendicitis, Histopathology, Appendiceal enterobius vermicularis, Parasitic infestations.
INTRODUCTION:Acute appendicitis is the most frequently observed disease requiring emergency surgery. (1) The incidence of appendectomy is 12% for men and 25% for women and the lifetime risk of acute appendicitis is 8.6% and 6.7% for men and women, respectively. (2) Appendicitis is primarily a disease of adolescents and young adults with a peak incidence in the second and third decade of life. (3) A variety of neoplastic and inflammatory conditions can mimic acute appendicitis. Parasites are one of the most uncommon causes of acute appendicitis. Enterobius vermiculats, ascaris lumbricoids, schistosoma spcies and Taenia species are the parasites that can lead to a clinical picture of acute appendicites. Enterobius vermicularis is the parasite that most frequently contributes to a clinical picture of acute appendicitis. (4,5) Clinical diagnosis of acute appendicitis is routinely done on history especially of migratory pain and elicitation of physical signs. Out of reported 250,000 appendectomies performed worldwide annually, about 15% are carried out on non-appendiceal pathologies. (6) In literature these is a consensus on luminal obstruction being the most common cause of acute appendicitis. Luminal obstruction is mostly caused by fecal impactions and lymphoid hyperplasia. (3,7,8) Appendiceal parasitosis is almost never suspected or diagnosed pre-