Acute Appendicitis after Liver Transplant: A Case Report and Review of the Literature

Andrade, Ronaldo; Pires, Rodrigo; Silva, Raul Évora; Mello, Felipe Pedreira Tavares de; Sousa, Cláudia Cristina Tavares de; Basto, Samanta Teixeira; Fernandes, Eduardo de Souza Martins

doi:10.4236/ojots.2014.44005

Cited by 4 publications

(21 citation statements)

References 5 publications

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“…Acute appendicitis is the most common cause of acute abdomen, with a peak incidence in the 2 nd and 3 rd decades of life. There is risk of 7% of a person presenting it during lifetime 3 , 6 . However, despite being relatively common condition in the general population, its appearance after liver transplantation is a rare condition, with few reports or studies in the literature; it has incidence ranging from 0.09% to 0.49% 3 , 11 .…”

Section: Discussionmentioning

confidence: 99%

“…The recent increase in solid organ transplants, as well as better surgical, drug and higher survival rate of transplant patients conditions, tend to significantly increase the number of cases reported in literature 3 , 7 .…”

Section: Discussionmentioning

confidence: 99%

“…In liver transplant patients the cause of appendicitis is not different from that found in patients not immunosuppressed, being the main causes mechanical obstruction and bacterial overgrowth. In addition to these causes, there were already described in literature lymphoid hyperplasia and infections by cytomegalovirus 2 , 3 , 7 .…”

Section: Discussionmentioning

confidence: 99%

“…Appendicitis is a common cause of surgical emergency, and in the population of patients undergoing organ transplantation it is rare 3 , 5 , 6 , 7 , 9 , 11 . In these cases it has often clinical presentation similar to non-transplant patients.…”

Section: Introductionmentioning

confidence: 99%

“…Complications from diagnostic delays are frequent, as well as the difficulty of making the differential diagnosis with other causes of acute abdomen. Only a few case reports and studies are present in literature 1 , 2 , 3 , 4 , 7 , 8 , 10 , 11 .…”

Section: Introductionmentioning

confidence: 99%

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Acute Apendicitis in Liver Transplant Recipients

Fonseca-Neto

Lima

Melo

et al. 2016

ABCD, arq. bras. cir. dig.

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Background : Appendicitis is a common cause of emergency surgery that in the population undergoing organ transplantation presents a rare incidence due to late diagnosis and treatment. Aim : To report the occurrence of acute appendicitis in a cohort of liver transplant recipients. Methods : Retrospective analysis in a period of 12 years among 925 liver transplants, in witch five cases of acute appendicitis were encountered. Results : Appendicitis occurred between three and 46 months after liver transplantation. The age ranged between 15 and 58 years. There were three men and two women. The clinical presentations varied, but not discordant from those found in non-transplanted patients. Pain was a symptom found in all patients, in two cases well located in the right iliac fossa (40%). Two patients had symptoms characteristic of peritoneal irritation (40%) and one patient had abdominal distention (20%). All patients were submitted to laparotomies. In 20% there were no complications. In 80% was performed appendectomy complicated by suppuration (40%) or perforation (40%). Superficial infection of the surgical site occurred in two patients, requiring clinical management. The hospital stay ranged from 48 h to 45 days. Conclusion : Acute appendicitis after liver transplantation is a rare event being associated with a high rate of drilling, due to delays in diagnosis and therapy, and an increase in hospital stay.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Acute Apendicitis in Liver Transplant Recipients

Fonseca-Neto

Lima

Melo

et al. 2016

ABCD, arq. bras. cir. dig.

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Emergency General Surgery in the Immunocompromised Surgical Patient

Tejiram

Sava

2018

Emergency General Surgery

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Acute appendicitis after liver transplantation: A single center experience and review of the literature

Jamtani

Kim

Lee

et al. 2020

Ann Hepatobiliary Pancreat Surg

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Backgrounds/Aims: Acute appendicitis is one of the most common emergent disease in the general population requiring surgical treatment. However, only a few cases of appendicitis after liver transplantation (LT) were reported. We described experiences of acute appendicitis after LT in single center. Methods: From March 1988 to July 2019, we reviewed retrospectively all the patients who diagnosed with acute appendicitis after LT at the Seoul National University Hospital. We described and analyzed clinical outcomes of appendectomy after LT. Results: A total of 12 patients out of 2,237 LT patients underwent appendectomy due to acute appendicitis. The mean age was 48±12 years. Nine patients (75%) underwent deceased donor liver transplantation (DDLT) and three patients (25%) underwent living donor liver transplantation (LDLT). The mean days from transplantation to the onset of acute appendicitis was 739 (range 57-4,496) days. Every patients underwent appropriate appendectomy within 1 days after visiting hospital. Leukocytosis was seen in three patients (25%). Seven patients (58%) underwent laparoscopic appendectomy and five patients (42%) underwent open appendectomy. The total operative time was 47.5 (range 25-135) minutes. The median postoperative hospitalization was 4 (range 2-11) days. There was no postoperative complications documented. There was no significant difference of clinical outcomes between laparoscopic appendectomy group and open appendectomy group. Conclusions: Early surgical management achieved satisfactory postoperative results without graft dysfunction after LT. Laparoscopic appendectomy also could be applicable with safe and feasible outcomes even in post-LT recipients.

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Acute Appendicitis after Liver Transplant: A Case Report and Review of the Literature

Cited by 4 publications

References 5 publications

Acute Apendicitis in Liver Transplant Recipients

Acute Apendicitis in Liver Transplant Recipients

Emergency General Surgery in the Immunocompromised Surgical Patient

Acute appendicitis after liver transplantation: A single center experience and review of the literature

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