Acute and sub-lethal toxicity of eight essential oils of commercial interest against the filariasis mosquito Culex quinquefasciatus and the housefly Musca domestica

Benelli, Giovanni; Pavela, Roman; Giordani, Cristiano; Casettari, Luca; Curzi, Giulia; Cappellacci, Loredana; Petrelli, Riccardo; Maggi, Filippo

doi:10.1016/j.indcrop.2017.12.062

Cited by 131 publications

(67 citation statements)

References 63 publications

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“…Many EOs and their components are known to exhibit antifeedant properties against a wide range of insect pests [ 4 , 5 ]. However, research papers on the effects of aniseed EO against stored grain pests are limited though other Apiaceae species were shown as source of insecticidal agents [ 9 , 52 , 53 ] and effective against T. castaneum [ 29 , 54 ]. The EO from Azilia eryngioides (Pau) Hedge and Lamond showed LC 50 values on Sitophilus granarius and T. castaneum of 20.05 μL/L and 46.48 μL/L, respectively, after a 24 h of treatment [ 55 ].…”

Section: Discussionmentioning

confidence: 99%

“…Among them, the usage of essential oils (EOs), which are complex mixture of small-sized, lipophilic and volatile compounds, appears to be very promising. EO of parsley family (i.e., Apiaceae or Umbelliferae) have been studied for their insecticidal properties [ 6 , 7 , 8 , 9 ] showing activity against a wide range of target insects, e.g., from stored grain to insect pests, owing to their documented ovicidal, larvicidal, and adulticidal toxicity [ 10 , 11 , 12 , 13 ]. Nevertheless, EOs-based pesticides can present some issues, as low water solubility, rapid environmental degradation, and lack of stability during storage [ 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

“…Overall, the insecticidal activity of EOs and their components are frequently assessed against insect pest species at the macromolecular level [ 9 ]. Nonetheless, the underlying mode of action of these EOs and their main constituents is still poorly understood with scarce studies exploring some biochemical targets and their mediated biochemical changes, such as the contents of total protein, total lipids, glucose, activity of aspartate aminotransferase (AST) and alanine aminotransferase (ALT).…”

Section: Introductionmentioning

confidence: 99%

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Pimpinella anisum Essential Oil Nanoemulsion Toxicity against Tribolium castaneum? Shedding Light on Its Interactions with Aspartate Aminotransferase and Alanine Aminotransferase by Molecular Docking

et al. 2020

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The insecticidal activity is the result of a series of complex interactions between toxic substances as ligands and insect’s enzymes as targets. Actually, synthetic insecticides used in pest control programs are harmful to the environment and may affect non-target organisms; thus, the use of natural products as pest control agents can be very attractive. In the present work, the toxic effect of aniseed (Pimpinella anisum L.) essential oil (EO) and its nanoemulsion (NE) against the red flour beetle Tribolium castaneum, has been evaluated. To assess the EO mode of action, the impact of sub-lethal concentrations of aniseed EO and NE was evaluated on enzymatic and macromolecular parameters of the beetles, including aspartate aminotransferase (AST), alanine aminotransferase (ALT), total protein, total lipids and glucose. Finally, a molecular docking study was conducted to predict the mode of action of the major EO and NE components namely E-anethole, Limonene, alpha-himalachalene, trans-Verbenol and Linalool at binding site of the enzymes AST and ALT. Herein, the binding location of the main compounds in both proteins are discussed suggesting the possible interactions between the considered enzymes and ligands. The obtained results open new horizons to understand the evolution and response of insect-plant compounds interactions and their effect predicted at the molecular levels and side effects of both animal and human.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Pimpinella anisum Essential Oil Nanoemulsion Toxicity against Tribolium castaneum? Shedding Light on Its Interactions with Aspartate Aminotransferase and Alanine Aminotransferase by Molecular Docking

et al. 2020

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“…However, essential oils are also known to cause a variety of sublethal effects that are detrimental to insect survival and reproduction. These effects include repellency, irritability, altered respiratory activity, changes in swimming pattern, and reduced adult emergence, longevity, fertility, fecundity and natality [49][50][51][52]. Future studies evaluating both the lethal and sublethal effects of L. scoparium essential oil, its fractions and emulsions could reveal the full spectrum of their biological effects against mosquitoes.…”

Section: Discussionmentioning

confidence: 99%

Leptospermum scoparium essential oil is a promising source of mosquito larvicide and its toxicity is enhanced by a biobased emulsifier

et al. 2020

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Synthetic pesticides are the cornerstone of vector-borne disease control, but alternatives are urgently needed to tackle the growing problem of insecticide resistance and concerns over environmental safety. Leptospermum scoparium J.R. Forst and G. Forst (manuka) essential oil and its four fractions were analyzed for chemical composition and toxicity against Aedes aegypti larvae. The use of bio-based amylose-N-1-hexadecylammonium chloride inclusion complexes (Hex-Am) as an emulsifier for L. scoparium essential oil was also investigated. Fraction 1 was inactive, fractions 2 (LC 50 = 12.24 ppm) and 3 (LC 50 = 20.58 ppm) were more toxic than the whole essential oil (LC 50 = 47.97 ppm), and fraction 4 (LC 50 = 35.87 ppm) had similar toxicity as the whole essential oil. Twenty-one chemical constituents were detected in L. scoparium essential oil compared to 16, 5, 19 and 25 chemical constituents in fractions, 1, 2, 3 and 4 respectively. The two most dominant chemical constituents were calamenene (17.78%) and leptospermone (11.86%) for L. scoparium essential oil, calamenene (37.73%) and ledene (10.37%) for fraction 1, leptospermone (56.6%) and isoleptospermone (19.73) for fraction 2, cubenol (24.30%) and caryophyllene oxide (12.38%) for fraction 3, and γ-gurjunene (21.62%) and isoleptospermone (7.88%) for fraction 4. Alpha-pinene, ledene, and aromandendrene were 2-7 times less toxic than the whole essential suggesting that the toxicity of L. scoparium essential oil was either due to other chemical constituents that were not tested or due synergist interactions among chemical constituents. Leptospermum scoparium essential oil-Hex-Am emulsion (LC 50 = 29.62) was more toxic than the whole essential oil. These findings suggest that L. scoparium essential oil is a promising source of mosquito larvicide and that Hex-Am is an excellent emulsifier for L. scoparium essential oil for use as a larvicide.

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“…In addition to the essential oil, these plants may contain alkaloids, saponins, flavonoids, quercetin, amino acids, minerals, pectins, tannins, mucilage, acetic and oxalic acids, coryandrol, limonene, linalool, terpinene and sugars. They are also considered promising candidates for biocides to control parasites and vectors [46].…”

Section: Apiaceaementioning

confidence: 99%

Current Status of the Occurrence and Reaction Root-knot Nematodes in the Main Botanical Families of Medicinal Plants

Costa

Santos

et al. 2019

JEAI

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Medicinal plants are described such as those produce substances capable of provoking reactions in the human body leading to the cure of diseases. Like as cultivated species, medicinal plants can be attacked by various pests and diseases, affecting the qualitative and quantitative characteristics of their curative properties, as well as productivity. Phytonematodes are one of the main factors limiting the productivity of cultivated plants. In medicinal species this pathogens group has caused damage in the sanity of the plants interfering in the quality of the compounds produced. Among them, due to the high parasitism degree, the species of the genus Meloidogyne, popularly known as root-knot nematodes. Among the management strategies of these phytopathogens, biological and cultural controls have low efficiency reports. Likewise, chemical control is not indicated due to its high cost, besides, its high toxicity and risk of environmental pollution. Therefore, the most effective control method is the use of resistant plant species or cultivars. Once these species are identified, they can be used as antagonists or incorporated into the soil, aiming to decrease the nematode population in infested areas. The use of resistant medicinal species allows little or no reproduction of Meloidogyne spp., providing effective control in the field. Other advantages are the reduction of production costs, and the protection of the environment against pollution caused by chemical waste.

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Acute and sub-lethal toxicity of eight essential oils of commercial interest against the filariasis mosquito Culex quinquefasciatus and the housefly Musca domestica

Cited by 131 publications

References 63 publications

Pimpinella anisum Essential Oil Nanoemulsion Toxicity against Tribolium castaneum? Shedding Light on Its Interactions with Aspartate Aminotransferase and Alanine Aminotransferase by Molecular Docking

Pimpinella anisum Essential Oil Nanoemulsion Toxicity against Tribolium castaneum? Shedding Light on Its Interactions with Aspartate Aminotransferase and Alanine Aminotransferase by Molecular Docking

Leptospermum scoparium essential oil is a promising source of mosquito larvicide and its toxicity is enhanced by a biobased emulsifier

Current Status of the Occurrence and Reaction Root-knot Nematodes in the Main Botanical Families of Medicinal Plants

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