Acute and short-term beetroot juice nitrate-rich ingestion enhances cardiovascular responses following aerobic exercise in postmenopausal women with arterial hypertension: A triple-blinded randomized controlled trial

Effects of short-term dietary nitrate supplementation on exercise and coronary blood flow responses in patients with peripheral artery disease

“…However, their patients consumed significantly less nitrate per week with lower frequency (i.e., 1 bottle/day on 3 days per week at 4.2 mmol per bottle) and participated in intermittent walking exercise after supplementation on those days, likely limiting plasma nitrate and nitrite accumulation. While the dose (two bottles/day) and frequency (4–6 consecutive days) of nitrate-rich juice consumption in our study is higher than most previous short-term supplementation studies in healthy and patient populations [typical doses have been 1 bottle/4–6 mmol per day over <7 days ( 65–67 )] these results suggest that PAD patients have the capacity to augment circulating nitrate and nitrite if supplemented daily and if steps to avoid oral anti-bacterial practices are closely followed. The ability to increase plasma nitrite could be particularly important for PAD patients who appear to have a reduced ability (relative to healthy adults) to increase skeletal muscle nitrate and nitrite stores ( 68 ).…”