Acute and chronic toxicity of a lyophilised aqueous extract of Tanacetum vulgare leaves in rodents

Étude de la toxicité aiguë et subchronique de l’extrait aqueux de <em>Passiflora foetida</em> Linn. (Passifloraceae) chez les rats et les souris

“…De même, elle n'est pas toxique par voie orale. Des variations de DL 50 en fonction de la voie d'administration et de l'espèce ont déjà été rapportées par Lahlou et al (2008) avec l'extrait aqueux lyophilisé de Tanacetum vulgare et par Amein et al (2008) avec la thymoquinone, principe actif issu de Nigella sativa.…”

Acute and sub-chronic oral toxicity studies of an aqueous stem bark extract of Pterocarpus soyauxii Taub (Papilionaceae) in rodents

“…A good correlation has been reported between toxicological insults in rats and humans, correlation is weaker between humans and mice (Olson et al, 2000). Therefore numerous studies investigate the acute effects of high doses in mice and the chronic effects of lower doses in rats including the doses potentially usable in humans (Rhiouani et al, 2008;Lahlou et al, 2008).…”

Acute and Subchronic Oral Toxicity Assessment of the Ethanolic Extract of the root of <i>Oncoba spinosa</i> (Flacourtiaceae) in Rodents

“…In fact, there is lack of evidence on quality, safety and efficacy of many herbal preparations. Although many herbal preparations are non-toxic, many plants currently used for medicines have been shown to be highly toxic when given either acutely or sub-chronically [3,4]. The increasing number of plant based medication users around the globe and lack of experimental reports on their safety make it basic to direct toxicological investigation on natural herbal products [5].…”