“…Future studies should be designed to identify optimally suited stimulation protocols with regard to the abovementioned parameters, and, given the positive results of the studies by Brunoni, Valiengo, et al (2013) and Valiengo et al (2013), it would make sense to conduct large multi-centre double-blinded sham-controlled trials. Apart from this, it might, furthermore, make sense to explore the potential of tDCS by elucidating the interaction of tDCS with antidepressant medication or medication known to improve the efficacy of anodal tDCS, such as D-cycloserine and reboxetine (Kuo et al, 2016;Nitsche, Jaussi, et al, 2004), combining tDCS with cognitive training of prefrontal functions, comparing the efficacy of different electrode positions directly, testing the impact of remote 'boosting' sessions of tDCS on the maintenance of therapeutic effects, broadening the application of tDCS to specific depression syndromes, such as post-stroke depression, and exploring the cognitive effect of tDCS in more detail. The results of these studies might help to identify optimized stimulation protocols, to learn more about the cognitive impact of tDCS in depression, and suitable patient groups.…”