Acute admissions of patients with sickle cell disease who live in Britain.

Brozović, Milica; Davies, Sally C.; Brownell, Alison

doi:10.1136/bmj.294.6581.1206

Cited by 99 publications

(45 citation statements)

References 14 publications

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“…Secondly, admissions were commonest at the peaks of summer heat and winter cold. Indeed, VOC is the quintessential feature of SCD and is the most common cause of hospitalization in different populations [7][8][9][10] . Therefore, when a SCD clinic was eventually established in 1994, emphasis was placed on counseling and health education.…”

Section: Discussionmentioning

confidence: 99%

Ten-Year Review of Hospital Admissions among Children with Sickle Cell Disease in Kuwait

Akar

Adekile

2008

Med Princ Pract

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Objective: This study was designed to document the common causes and patterns of hospitalization among sickle cell disease (SCD) patients in Kuwait. Subjects and Methods: The case files of all SCD patients admitted to the hospital between 1995 and 2004 were studied. Their personal data, hemoglobin genotype, diagnosis on admission, complete blood count, treatment received, length of stay and outcome were documented. Results: Fifty SCD patients aged from 10 months to 14.8 years (mean: 8.7 ± 2.8 years) had 351 admissions over the 10-year period accounting for 0.6% of all admissions to the pediatric wards. The 50 patients were made up of 18 Hb SS, 28 Sβ⁰thal and 4 Hb SD patients. Common causes of admission were vaso-occlusive crisis: 222 (63.2%), acute splenic sequestration crisis: 32 (9.1%), hemolytic crisis: 31 (8.8%) and acute chest syndrome: 23 (6.6%). Stroke was seen in only 1 patient, and bacteriologically proven (Salmonella) acute osteomyelitis in 1 patient. There were no deaths during the study period. Conclusions: Vaso-occlusive crisis was the commonest cause of hospitalization among our SCD patients. Efforts should be intensified to give advice on preventive measures. The use of hydroxyurea should be encouraged in patients with frequent severe pain crises.

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Section: Discussionmentioning

confidence: 99%

Ten-Year Review of Hospital Admissions among Children with Sickle Cell Disease in Kuwait

Akar

Adekile

2008

Med Princ Pract

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“…Painful crises are the dominant feature of sickle cell disorders both for individual suffering and for service use 1. In the United States most painful episodes are managed at home, 2 3 and many patients with sickle cell disease do not normally use health services for management of pain 2.…”

Section: Introductionmentioning

confidence: 99%

Experiences of hospital care and treatment seeking for pain from sickle cell disease: qualitative study

Maxwell

Streetly

Bevan

1999

BMJ

146

138

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Objective To investigate how sociocultural factors influence management of pain from sickle cell disease by comparing the experiences of those who usually manage their pain at home with those who are more frequently admitted to hospital for management of their pain. Design Qualitative analysis of semistructured individual interviews and focus group discussions. Participants 57 participants with genotype SS or S/ -thal (44 subjects) or SC (9) (4 were unknown). 40 participants took part in focus groups, six took part in both focus groups and interviews, and nine were interviewed only. Participants were allocated to focus groups according to number of hospital admissions for painful crisis management during the previous year, ethnic origin, and sex. Results The relation between patients with sickle cell disease and hospital services is one of several major non-clinical dimensions shaping experiences of pain management and behaviour for seeking health care. Experiences of hospital care show a range of interrelated themes, which are common to most participants across variables of sex, ethnicity, and hospital attended: mistrust of patients with sickle cell disease; stigmatisation; excessive control (including both over-and undertreatment of pain); and neglect.

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“…The other physical complications of SCD include delayed growth and sexual maturation, acute and chronic pulmonary dysfunction, aseptic necrosis of the hips or shoulders requiring artificial joint replacements, leg ulcers, fertility problems, priapism, gynaecological and obstetric problems, and death due to multiple organ system failures. A small minority of patients require lengthy admission several times a year, with the result that a substantial part of their life is spent in hospital (Brozovic et al, 1987).…”

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confidence: 99%

Adults with sickle cell disease: Psychological impact and experience of hospital services

Harris¹,

Parker

Barker

1998

Psychology, Health & Medicine

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Acute admissions of patients with sickle cell disease who live in Britain.

Cited by 99 publications

References 14 publications

Ten-Year Review of Hospital Admissions among Children with Sickle Cell Disease in Kuwait

Ten-Year Review of Hospital Admissions among Children with Sickle Cell Disease in Kuwait

Experiences of hospital care and treatment seeking for pain from sickle cell disease: qualitative study

Adults with sickle cell disease: Psychological impact and experience of hospital services

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