“…These side effects will adversely affect the patient's short and long-term prognosis [ 10 ]. In addition, before prescribing imatinib in the neoadjuvant course for 6 to 12 months, the risks of major complications related to spontaneous evolution of the jejunal GIST (rupture, perforation, and hemorrhage) must be considered [ [11] , [12] , [13] ]. Finally, whereas locally advanced jejunal GISTs have shown similarities with their analogs in the stomach, clinical evolution appears to be less favorable [ 14 , 15 ].…”