Acupuncture with specific mode electro-stimulation effectively and transiently opens the BBB through Shh signaling pathway
Yubo Lin,
Lin Gan,
Li Ren
et al.
Abstract:To explore a new method that patients with brain diseases such as stroke sequelae are hindered by blood-brain barrier (BBB) in clinical treatment. Research preliminarily found that acupuncture with specific mode electro-stimulation (EA) to open BBB-assisted drug delivery may be is an effective means to improve the clinical efficacy of brain disease patients. So here we further explore the features and mechanism. Middle cerebral artery occlusion/R recovery rats were employed as the animal model. Laser Doppler m… Show more
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