Abstract:Limited evidence exists for the effectiveness of acupuncture as a symptomatic treatment of ADHD. Given that the risk of bias of the included studies was high, firm conclusions cannot be drawn.
“…A review article published in 2011 assessed the efficacy and safety of acupuncture as a treatment for ADHD; however, no conclusions could be drawn from it because no studies met the inclusion criteria [25]. Furthermore, a meta-analysis conducted in 2011 included 3 RCTs with different interventions and control designs; these differences limited the ability to draw concrete conclusions from the data [26]. The latest systematic review regarding acupuncture for ADHD was published in 2015.…”
Section: Discussionmentioning
confidence: 99%
“…The ER is defined as the proportion of participants that experienced at least some improvement after receiving the intervention; however, the method for assessing the ER may deviate from the judgement criteria for defining improvement and the subjective consciousness of the assessors, resulting in difficulties and bias when comparing results with other studies. Nevertheless, many clinical trials assessing acupuncture still use efficiency as the result evaluation and some system review articles also use ER as the main outcome [26, 41]. However, it will remain necessary to standardize the outcome measurements of ADHD to assess specific outcomes in future studies.…”
Section: Discussionmentioning
confidence: 99%
“…A systematic review conducted in 2011 did not yield any conclusions on the efficacy and safety of AT for ADHD due to a lack of studies that met the inclusion criteria [25]. Two meta-analyses conducted in 2011 [26] and 2015 [27] included RCTs with different interventions and complex control designs; these studies provided limited reliable data regarding the efficacy of AT, which thereby remains controversial. Therefore, this study sought to update the literature and compare the efficacy of AT with that of MPH in children and adolescents with ADHD.…”
<b><i>Background:</i></b> This study aimed to assess the efficacy of acupuncture for treating attention deficit hyperactivity disorder (ADHD) in children and adolescents. <b><i>Patients and Methods:</i></b> Systematic review and meta-analysis including randomized controlled trials that compared the effects of acupuncture treatment (AT) with pharmacotherapy (methylphenidate hydrochloride, MPH) among patients with ADHD. A total of 12 electronic databases were searched from inception until February 3, 2020. The main outcomes were the effective rate and post-treatment hyperactivity scores. We also assessed the incidence of adverse events and follow-up course. <b><i>Results:</i></b> A total of 10 studies involving 876 patients were included in this study. The meta-analysis revealed that AT yielded a significantly higher effective rate than MPH (odds ratio 2.239, 95% CI 1.438–3.487, <i>p</i> < 0.001, 8 studies), and that AT can reduce the hyperactivity scores to a lesser degree than MPH (standardized mean difference = –0.882, 95% CI –1.295 to –0.469, <i>p</i> < 0.001, 3 studies). Two studies reported no adverse events in the AT group, while one study suggested that AT can reduce adverse drug reactions. Furthermore, 3 studies concluded that the effects of AT were maintained, even after completion of treatment. <b><i>Conclusion:</i></b> This study suggests that AT may be more beneficial than MPH therapy for ADHD patients. However, the evidence may be highly limited, especially considering the outcome of hyperactivity scores with the high risk of bias, very low GRADE, and small number of studies. Thus, further studies of rigorous design and high quality are needed to confirm and strengthen the results, especially in the Western part of the world. Additionally, well-designed randomized controlled trials that evaluate adverse events and include a long-term follow-up should be conducted to determine the efficacy, safety, and side effects of AT for ADHD in children and adolescents.
“…A review article published in 2011 assessed the efficacy and safety of acupuncture as a treatment for ADHD; however, no conclusions could be drawn from it because no studies met the inclusion criteria [25]. Furthermore, a meta-analysis conducted in 2011 included 3 RCTs with different interventions and control designs; these differences limited the ability to draw concrete conclusions from the data [26]. The latest systematic review regarding acupuncture for ADHD was published in 2015.…”
Section: Discussionmentioning
confidence: 99%
“…The ER is defined as the proportion of participants that experienced at least some improvement after receiving the intervention; however, the method for assessing the ER may deviate from the judgement criteria for defining improvement and the subjective consciousness of the assessors, resulting in difficulties and bias when comparing results with other studies. Nevertheless, many clinical trials assessing acupuncture still use efficiency as the result evaluation and some system review articles also use ER as the main outcome [26, 41]. However, it will remain necessary to standardize the outcome measurements of ADHD to assess specific outcomes in future studies.…”
Section: Discussionmentioning
confidence: 99%
“…A systematic review conducted in 2011 did not yield any conclusions on the efficacy and safety of AT for ADHD due to a lack of studies that met the inclusion criteria [25]. Two meta-analyses conducted in 2011 [26] and 2015 [27] included RCTs with different interventions and complex control designs; these studies provided limited reliable data regarding the efficacy of AT, which thereby remains controversial. Therefore, this study sought to update the literature and compare the efficacy of AT with that of MPH in children and adolescents with ADHD.…”
<b><i>Background:</i></b> This study aimed to assess the efficacy of acupuncture for treating attention deficit hyperactivity disorder (ADHD) in children and adolescents. <b><i>Patients and Methods:</i></b> Systematic review and meta-analysis including randomized controlled trials that compared the effects of acupuncture treatment (AT) with pharmacotherapy (methylphenidate hydrochloride, MPH) among patients with ADHD. A total of 12 electronic databases were searched from inception until February 3, 2020. The main outcomes were the effective rate and post-treatment hyperactivity scores. We also assessed the incidence of adverse events and follow-up course. <b><i>Results:</i></b> A total of 10 studies involving 876 patients were included in this study. The meta-analysis revealed that AT yielded a significantly higher effective rate than MPH (odds ratio 2.239, 95% CI 1.438–3.487, <i>p</i> < 0.001, 8 studies), and that AT can reduce the hyperactivity scores to a lesser degree than MPH (standardized mean difference = –0.882, 95% CI –1.295 to –0.469, <i>p</i> < 0.001, 3 studies). Two studies reported no adverse events in the AT group, while one study suggested that AT can reduce adverse drug reactions. Furthermore, 3 studies concluded that the effects of AT were maintained, even after completion of treatment. <b><i>Conclusion:</i></b> This study suggests that AT may be more beneficial than MPH therapy for ADHD patients. However, the evidence may be highly limited, especially considering the outcome of hyperactivity scores with the high risk of bias, very low GRADE, and small number of studies. Thus, further studies of rigorous design and high quality are needed to confirm and strengthen the results, especially in the Western part of the world. Additionally, well-designed randomized controlled trials that evaluate adverse events and include a long-term follow-up should be conducted to determine the efficacy, safety, and side effects of AT for ADHD in children and adolescents.
Introduction: Dry needling: e.t. Acupuncture: is one of the most accepted CAM therapies, most well: known branch of the Traditional Chinese Medicine, which ��� intensive research a few decades in the US, Europe, even in China. Is backed by proving research results of Evidence Based Medicine for properly as well.
“…Researchers have tried to treat ADHD patients with acupuncture and achieved remarkable clinical effects. [ 6 , 7 ] Cochrane Collaboration [ 8 ] and Lee et al [ 9 ] conducted a systematic review and meta-analysis of acupuncture treatment for ADHD in 2010 respectively. The former performed a descriptive analysis of the included studies and the meta-analysis of only 3 included studies.…”
Background:
Attention Deficit Hyperactivity Disorder (ADHD) is the most common behavioral disorder in childhood. Acupuncture treatment of ADHD has formed a relatively systematic theoretical and clinical treatment system which achieved satisfactory results. However, there has been no systematic evaluation of its effectiveness and safety. The purpose of this study was to evaluate the efficacy and safety of acupuncture in the treatment of ADHD.
Methods:
A systematic search of literature will be conducted in PubMed, Cochrane Library, the Web of Science, Excerpt Medica Database, Chinese Biomedical Literature Database, VIP, Wanfang database, China National Knowledge Infrastructure database for articles published up to September, 2019. The searching terms include “attention deficit”, “hyperactivity”, “mild brain dysfunction”, “acupuncture”, “electroacupuncture”. The search is limited to studies published in Chinese and English. Two reviewers will extract and evaluate the information independently. Cochrane Collaboration tool and Jadad scale will be used to evaluate the quality of the studies. Review Manager Version 5.3 (Cochrane Collaboration's software) will be used to carry out the meta-analysis.
Results:
High-quality synthesis and/or descriptive analysis of current evidence will be provided from effective rate, total score of traditional Chinese medicines syndromes, conners child hyperactivity-diagnosis rating scale, conners index of hyperactivity, the recurrence rate, and adverse events.
Conclusion:
This study will provide the evidence of whether acupuncture is an effective and safe intervention to ADHD.
INPLASY registration number:
INPLASY202140022
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