Acupuncture for the treatment of dry eye

Abstract

Background: As a common ophthalmic disease, dry eye (DE) may bring several adverse effects on the quality of life for patients. In recent years, Acupuncture (AC) is becoming increasingly popular for treating DE. Thus, we conceived this systematic review aims to evaluate the effectiveness and safety of AC for DE objectively. Methods: The search results are restricted to randomized controlled trials and human studies. We will establish the inclusion criteria through discussion and design a detailed literature search strategy for each database. Articles are searched from 4 English databases (the Cochrane Library, PubMed, Web of Science, and EMBASE) and 4 Chinese databases (Wangfang, China National Knowledge Infrastructure, Chinese Biomedical Literature Database, and Chinese scientific and technical journals database). The relevant studies published from the date of database inception until January 2020 will be collected. We will also search (International Clinical Trials Registry Platform), PROSPERO, and potential gray literature. Two reviewers independently perform literature screening, information extraction, and assessment of study quality. The outcome measures include primary outcome measures (Schirmer I test and break-up time), secondary outcome measures (Ocular Surface Disease Index, corneal fluorescein staining, and tear osmolarity), and safety outcome measures. Assessment of bias risk and data processing are performed using RevMan 5.3 software ( the Nordic Cochrane Centre, Copenhagen, Denmark). Results: We will evaluate the curative effect of AC for DE comprehensively based on multiple outcome measures. Conclusion: This systematic review will provide evidence for the effectiveness and safety of AC in the treatment of DE. PROSPERO number: CRD42019144790

Effectiveness and safety review of Chinese herbal sachets for external use in the treatment of COVID-19 pandemic

“…Otherwise, after excluding trials with significant clinical heterogeneity and sensitivity analysis, a random effects model will be used. [ 11 – 12 ] Grading of Recommendations, Assessment, Development and Evaluation (GRADE) will be used to determine confidence in the effect estimates.…”

“…The comparison can be sham Chinese herbal sachets with standard common therapy or standard common therapy without additional intervention. [ 10 – 11 ] Detailed steps will be followed as Figure 1 .…”

Severe Adverse Events of Periocular Acupuncture: A Review of Cases

“…Acupuncture is a traditional treatment method developed in East Asia over a significant period of time and is now recognized as an important component of complementary and alternative medicine worldwide [1][2][3].…”

“…In the field of ophthalmology, papers have been published on the effectiveness of acupuncture for some ophthalmologic diseases, and meta-analysis of diseases, such as dry eye syndrome, glaucoma, slowing myopia progression, amblyopia, and acute hordeolum, have been published or are in progress [2][3][4][5][6][7][8]. Recently, several studies, including meta-analysis, regarding dry eye syndrome have been reported and are in the spotlight [4,5,9].…”