Acupuncture Decreases Matrix Metalloproteinase-2 Activity in Patients with Migraine

Çayır, Yasemin; Özdemir, Gökhan; Çelik, Mine; Aksoy, Hülya; Aktürk, Zekeriya; Laloğlu, Esra; Akçay, Fatih

doi:10.1136/acupmed-2014-010612

Cited by 29 publications

(18 citation statements)

References 32 publications

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“…Acupuncture treatment could also significantly decrease matrix metalloproteinase-2 (MMP-2) activity in patients with migraine without affecting the MMP-2 concentrations. The analgesic effect of acupuncture might be associated with this decrease [54]. Acupuncture combined with electroacupuncture could decrease plasma glutamate levels, which were found significantly increased in rats during acute migraine attacks, and thereby relieving pain [55].…”

Section: Discussionmentioning

confidence: 99%

The Effectiveness of Acupuncture Combined with Tuina Therapy in Patients with Migraine

et al. 2019

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Background: This study aimed to explore the effectiveness of acupuncture combined with tuina therapy in patients with migraine. Methods: A prospective, randomized controlled assessor-blind clinical trial was performed between January 2017 and May 2018, and 135 patients were assigned into acupuncture combined with tuina (A), acupuncture (B), and control (flunarizine hydrochloride) (C) groups, each with 45 patients. Treatments were performed for 12 weeks and a 4-week follow-up. Frequency of attacks, severity of pain, duration of migraine, associated symptoms, patient-reported outcome (PRO) scores, and frequency of analgesic consumption were assessed. Results: The total effective rate was 95.6, 88.9, and 75.6% for group A, B, and C, respectively, with a significant reduction in attack frequency, severity of pain, duration of migraine, and associated symptoms at post-treatment and follow-up compared to pre-treatment. The PRO scores and frequency of analgesic consumption were significantly improved (group A, p < 0.01; groups B and C, p < 0.05). The differences in pre-/post-treatment and in pre-treatment/follow-up in groups A and B were significantly improved compared to group C (A vs. C, p < 0.01; B vs. C, A vs. B, p < 0.05). No significant adverse events occurred. Conclusion: Acupuncture combined with tuina could significantly increase the therapeutic effect of acupuncture in migraine treatment.

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Section: Discussionmentioning

confidence: 99%

The Effectiveness of Acupuncture Combined with Tuina Therapy in Patients with Migraine

et al. 2019

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“…[11] There are also studies showing the efficacy of acupuncture in reducing the number of migraine attacks. [12,13] Some authors also reported that acupuncture accelerated healing process, resolved edema, and provided analgesia in a case of metatarsal fracture. [14] In conclusion, to the best of our knowledge, this is the first case report to show the effectiveness of acupuncture in the treatment of venous insufficiency and varicose veins.…”

Section: Discussionmentioning

confidence: 99%

Application of acupuncture in the treatment of venous insufficiency and varicose veins

Alp¹

2020

Cardiovasc Surg Int

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A 43-year-old male patient was admitted with swollen legs, which was prominent in the right leg. He was under treatment for varicose veins due to femoral and saphenous insufficiency for 10 years. Edema, redness, and cyanosis were present in his toes on physical examination. According to the pulse examination, organ meridians with reduced energy were applied to the body acupuncture needles (Liv-3, St-41, Kid-6, St-25,24, Sp-9). The ear was stabbed in the ankle, Shen men's point. Diet for weight control of the leg was suggested. Thanks to the most effective acupuncture points for edema resolution, the measurements yielded a 4-cm decrease in the tibia plateau and 3-cm decrease in the ankle circumference. The patient's pain and cyanosis decreased. Local acupuncture was applied around the contracture as the patient's complaints diminished. In conclusion, acupuncture as a holistic approach can be a useful method in the treatment of venous insufficiency and varicose veins.

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“…16 Studies have assessed neurovascular blood flow via Doppler imaging studies 17,18 ; function and structure of the resting brain of migraine patient pre-and postacupuncture using functional magnetic resonance imaging (MRI) 19 ; and neurobiological changes secondary to acupuncture. [20][21][22] These studies seek to further qualify the various physiological effects that acupuncture have on the brain and migraine headache.…”

Section: Neurobiological Mechanisms On Use Of Acupuncturementioning

confidence: 99%

“…In sum, these studies appear to establish reasonable safety and efficacy of acupuncture for treatment of migraines in adults. 21 Additional research targeting various types of acupuncture for both acute and preventive treatments of migraine in adults and children are reviewed later.…”

Section: Neurobiological Mechanisms On Use Of Acupuncturementioning

confidence: 99%

Acupuncture in Adult and Pediatric Headache: A Narrative Review

et al. 2019

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Headaches in children and adolescents remain a very common problem with migraine being the most common headache disorder to present to medical attention. The approach to the treatment of migraine in children has consisted of treatment with acute and preventive medications, combined with lifestyle modification and behavioral interventions, such as cognitive behavioral therapy. With increasing frequency, complementary and alternative medicine (CAM) approaches, including acupuncture, are often recommended in the pediatric population to address significant disability with limited evidence-based treatment options. In this article, the authors conduct a review of acupuncture in pediatric headache, including neurobiological mechanisms, adult headache studies, pediatric headache studies, safety, and use of acupuncture in other conditions in children. This article aims to summarize the currently available evidence with which to recommend acupuncture in children for the adjunctive treatment of headache. Acupuncture appears to be safe and effective for the treatment of migraine in children.

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Acupuncture Decreases Matrix Metalloproteinase-2 Activity in Patients with Migraine

Abstract: Objective To evaluate the effect of acupuncture on the serum matrix metalloproteinase-2 (MMP-2) level and activity in patients with migraine.

Cited by 29 publications

References 32 publications

The Effectiveness of Acupuncture Combined with Tuina Therapy in Patients with Migraine

The Effectiveness of Acupuncture Combined with Tuina Therapy in Patients with Migraine

Application of acupuncture in the treatment of venous insufficiency and varicose veins

Acupuncture in Adult and Pediatric Headache: A Narrative Review

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