Acupuncture decreased the risk of coronary heart disease in patients with fibromyalgia in Taiwan: a nationwide matched cohort study

Wu, Mei-Yao; Huang, Mingcheng; Chiang, Jen‐Huai; Sun, Mao-Feng; Lee, Yu‐Chen; Yen, Hung-Rong

doi:10.1186/s13075-017-1239-7

Cited by 13 publications

(9 citation statements)

References 44 publications

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“…A modern medical study indicated that acupuncture can significantly increase blood flow in the skin and muscles of patients with FM,35 which is very important for reducing pain symptoms. As a primary mechanism of FM, the central sensitization of nervous system can decrease the pressure pain threshold, elicit hyperalgesia, and as a result, a noxious stimulus can cause more severe pain than in normal individuals 36,37. One recent animal study found that the upregulation of transient receptor potential vanilloid 1 and the phosphoactivation of extracellular signal regulated kinase were associated with mechanical hyperalgesia in FM model mice.…”

Section: Discussionmentioning

confidence: 99%

<p>Acupuncture therapy for fibromyalgia: a systematic review and meta-analysis of randomized controlled trials</p>

Zhang¹,

Chen²,

Xu³

et al. 2019

JPR

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PurposeFibromyalgia (FM) can cause chronic widespread pain and seriously affect the quality of patient lives. Acupuncture therapy is widely used for pain management. However, the effect of acupuncture on FM is still uncertain. The aim of this review was to determine the effect and safety of acupuncture therapy on the pain intensity and quality of life in patients with FM.Materials and methodsWe searched PubMed, the Cochrane Library, Embase, the China National Knowledge Infrastructure, the Chinese Science and Technology Periodical Database, and the Chinese Biomedical Literature Database to collect randomized controlled trials (RCTs) of acupuncture for FM published before May 2018. A meta-analysis was performed according to the Cochrane systematic review method by using RevMan 5.3 software, and GRADE was used to evaluate the quality of the evidence.ResultsWe identified 12 RCTs that compared acupuncture therapy to sham acupuncture or conventional medication. Meta-analysis showed that acupuncture was significantly better than sham acupuncture for relieving pain (MD =−1.04, 95% CI [−1.70, –0.38], P=0.002, I2=78%) and improving the quality of life (MD =−13.39, 95% CI [−21.69, –5.10], P=0.002, I2=82%), with low- to moderate-quality evidence in the short term. At follow-up in the long term, the effect of acupuncture was also superior to that of sham acupuncture. No serious adverse events were found during acupuncture.ConclusionAcupuncture therapy is an effective and safe treatment for patients with FM, and this treatment can be recommended for the management of FM.

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Section: Discussionmentioning

confidence: 99%

<p>Acupuncture therapy for fibromyalgia: a systematic review and meta-analysis of randomized controlled trials</p>

Zhang¹,

Chen²,

Xu³

et al. 2019

JPR

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“…All public insurance systems were integrated into the National Health Insurance (NHI) program in Taiwan in 1995 as a single-pay program to serve all residents, with 99% of 23.74 million residents covered in 2009. It has offered insurance cover for Traditional Chinese Medicine (TCM, including; Chinese herbal medicines, acupuncture, and traumatology manipulative therapies) and conventional Western medicine (17,18). Intact registration files and original claim data of acupuncture utilization were collected in the Taiwanese National Health Insurance Research Database (NHIRD).…”

Section: Introductionmentioning

confidence: 99%

Long-Term Effect of Acupuncture on the Medical Expenditure and Risk of Depression and Anxiety in Migraine Patients: A Retrospective Cohort Study

Liao

Lin

et al. 2020

Front. Neurol.

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Background: Migraine, a common neurological disorder, increases the risk of psychiatric disorders. Currently, the efficacy of conventional therapies is considered unsatisfactory. Acupuncture has been gaining popularity in treatment of neuropsychiatric disease. This study aimed to investigate the effect of acupuncture on medical expenditure and the risk of depression and anxiety in migraine patients. Methods: Patients with migraine were either selected for acupuncture treatment or no treatment based on the 1:1 propensity score-matched method from the Taiwanese National Health Insurance Research Database between 2000 and 2012 and followed up until the end of 2013. The observed outcome measures were comparison of medical expenditure and incidence of depression/anxiety in the two cohorts. Results: The acupuncture cohort had a lower medical expenditure within 1 year of the intervention than the non-acupuncture cohort (p < 0.001). The acupuncture cohort had a reduced risk of depression [adjusted hazard ratio [HR], 0.61, 95% confidence interval [CI], 0.39-0.95] and anxiety (adjusted HR, 0.51, 95% CI, 0.43-0.59) after adjusting for sex, age, monthly income, urbanization level, occupation category, baseline comorbidities, and medicines used. The Kaplan-Meier analysis revealed that the cumulative incidence of depression and anxiety was significantly lower in the acupuncture cohort than in the non-acupuncture cohort during the 13-year follow-up period (log-rank test, p < 0.001). Conclusions: Acupuncture could reduce medical expenditure and the risk of depression and anxiety during the long-term follow-up period in migraine patients. However, the regulatory effects and mechanisms should be assessed in further clinical research.

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“…The NHI program covers not only Western medical services but also ambulatory care in TCM. All claims data from the NHI program are collected in the National Health Insurance Research Database (NHIRD), and researchers can use these datasets to evaluate the utilization of TCM for various diseases such as allergies [ 14 , 15 ], musculoskeletal diseases [ 16 – 18 ], metabolic disorders [ 19 , 20 ], gynecologic diseases [ 21 ], pediatric diseases [ 2 ], geriatric disorders [ 22 ] and cancer [ 23 , 24 ]. De-identified demographic characteristics (e.g., sex, date of birth, occupation and place of residence) and clinical information (e.g., diagnosis, management and treatment) are also provided in the database.…”

Section: Introductionmentioning

confidence: 99%

Trends in use of acupuncture among adults in Taiwan from 2002 to 2011: A nationwide population-based study

Lee

Lin

et al. 2018

PLoS ONE

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In recent years, acupuncture has gained in popularity worldwide. However, recent epidemiological studies are lacking. We conducted this study to investigate the trends in acupuncture utilization among adults in Taiwan from 2002 to 2011. We analyzed data from the Longitudinal Health Insurance Database 2000 (LHID 2000), which contains all original claims data for 1 million beneficiaries randomly sampled from the registry of all beneficiaries enrolled in the National Health Insurance (NHI) program in 2000. The one-year prevalence of acupuncture use among adults increased from 7.98% in 2002 to 10.9% in 2011. Acupuncture use significantly increased yearly (incidence rate ratio = 1.04, 95% CI = 1.03−1.05, p<0.001). Patients who were female, were middle-aged, resided in highly urbanized areas and suffered from injury or disorders of the musculoskeletal system were prone to more frequent acupuncture use. Our study revealed that the utilization of acupuncture became increasingly popular in Taiwan from 2002 to 2011. Our findings may provide useful information for clinical practice and research as well as for health policy decision making.

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Acupuncture decreased the risk of coronary heart disease in patients with fibromyalgia in Taiwan: a nationwide matched cohort study

Cited by 13 publications

References 44 publications

<p>Acupuncture therapy for fibromyalgia: a systematic review and meta-analysis of randomized controlled trials</p>

<p>Acupuncture therapy for fibromyalgia: a systematic review and meta-analysis of randomized controlled trials</p>

Long-Term Effect of Acupuncture on the Medical Expenditure and Risk of Depression and Anxiety in Migraine Patients: A Retrospective Cohort Study

Trends in use of acupuncture among adults in Taiwan from 2002 to 2011: A nationwide population-based study

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