“…29,38,41,44 However, adverse effects, including fatigue, pruritus, nausea, sensitivity to cold, pain, itchiness, low energy, twitching, bleeding at acupoints, and abnormal electrocardiography and white blood cell count, were reported in three trials. 11,14,46 Appraisal of the quality of included studies is reported in Appendix 4, available online at http://links.lww.com/AOG/A760. Only one study achieved a low risk of bias in all domains.…”