Acupuncture accelerates recovery after general anesthesia: a prospective randomized controlled trial

Gemma, Marco; Nicelli, Elisa; Gioia, Luigi; Moizo, Elena; Beretta, Luigi; Calvi, Maria Rosa

doi:10.1016/s2095-4964(15)60159-5

Cited by 19 publications

(12 citation statements)

References 18 publications

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“…However, how acupuncture functions in disease treatments is still largely unknown. Acupuncture especially has specific functions in the treatment of ischemic heart diseases [ 2 – 5 ]. A variety of mechanisms likely explain the therapeutic effect of acupuncture on ischemic heart disease, including decreasing lipid peroxidation, facilitating energy metabolism and myocardial enzyme activity, influencing cellular ultrastructure, inhibiting apoptosis, improving cell genesis, and reducing myocardial oxygen demand [ 6 – 10 ].…”

Section: Introductionmentioning

confidence: 99%

Electroacupuncture Ameliorates the Coronary Occlusion Related Tachycardia and Hypotension in Acute Rat Myocardial Ischemia Model: Potential Role of Hippocampus

Cao

Zhang³

et al. 2015

Evidence-Based Complementary and Alternative Medicine

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Mechanisms for electroacupuncture (EA) in disease treatments are still enigmatic. Here, we studied whether hippocampus was involved in the protection of EA stimulation on myocardial ischemia injury. Acute myocardial ischemia (AMI) model was produced. EA stimulation at heart meridian from Shenmen (HT7) to Tongli (HT5) was applied to rats 3 times a day for continuous three days. Coronary occlusion related tachycardia and hypotension, indicated by heart rate, mean arterial pressure, and rate pressure product, were apparently impaired after AMI injury. By contrast, EA stimulating could ameliorate the impairments of heart function (P < 0.05). Interestingly, lesion of CA1 region of hippocampus abolished the protection of EA. Neuronal activity in CA1 area was affected by AMI. As evidenced, cell counts, cell types, and frequency of the discharged neurons were facilitated after AMI, while EA stimulation attenuated the abnormalities. Furthermore, c-Fos expression was significantly facilitated in CA1 area after AMI, which was reduced by EA stimulation. Correlations were established between c-Fos expression and cell counts of discharged neurons, as well as between heart function and cell counts of discharged neurons. Taken together, EA stimulation at heart meridian protects against heart dysfunction induced by AMI possibly through suppressing the neuronal activity in CA1 region.

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Section: Introductionmentioning

confidence: 99%

Electroacupuncture Ameliorates the Coronary Occlusion Related Tachycardia and Hypotension in Acute Rat Myocardial Ischemia Model: Potential Role of Hippocampus

Cao

Zhang³

et al. 2015

Evidence-Based Complementary and Alternative Medicine

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“…Meta-analytic evidence from 7 studies with 540 patients indicates that acupuncture is efficient and safe for improving recovery after colorectal cancer surgery, namely time to first flatus and time to first defecation 20 . Additionally, in patients undergoing ophthalmic surgeries, acupuncture was shown to reduce time to spontaneous eye opening, time to extubation, and time to follow commands when compared to sham or control 21 . To prevent adverse events from electrical currents, the use of bipolar laparoscopic systems is preferable.…”

Section: Discussionmentioning

confidence: 99%

Acupuncture reduces the time from extubation to ‘ready for discharge’ from the post anaesthesia care unit: results from the randomised controlled AcuARP trial

Fleckenstein

Baeumler

Gurschler

et al. 2018

Sci Rep

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Acupuncture may improve peri-operative care as it reduces post-operative symptoms, such as pain, nausea and vomiting, or sedation. This patient-assessor blinded, randomised trial in 75 women undergoing gynaecologic laparoscopy evaluated the effects of acupuncture combined with a standardised anaesthetic regimen (ACU) on post-anaesthetic recovery, when compared to acupressure (APU) or standard anaesthesia alone (CON). Main outcome measure was the time from extubation to ‘ready for discharge’ from recovery as assessed by validated questionnaires. The main outcome differed significantly between groups (p = 0.013). Median time to ready for discharge in the ACU group (30 (IQR: 24–41) min) was 16 minutes (35%) shorter than in the CON group (46 (36–64) min; p = 0.015) and tended to be shorter than in the APU group (43 (31–58) min; p = 0.08). Compared to CON (p = 0.029), median time to extubation was approximately 7 minutes shorter in both, the ACU and the APU group. No acupuncture or acupressure-related side-effects could be observed. A difference in time to recovery of 16 minutes compared to standard alone can be considered clinically relevant. Thus, results of this study encourage the application of acupuncture in gynaecological laparoscopy as it improves post-anaesthetic recovery.

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“…In addition, acupuncture anesthesia can reduce the accumulation of Ca 2+ in brain neurons, prevent Ca 2+ overload, mitigate or avoid necrosis of the neurons, and have a protective effect on the ischemic injury of neurons. As a result, the occurrence of cognitive impairment is decreased ( 20 ).…”

Section: Discussionmentioning

confidence: 99%

Combined acupuncture and general anesthesia on immune and cognitive function in elderly patients following subtotal gastrectomy for gastric cancer

Wang

2017

Oncol Lett

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This study investigated the effects of acupuncture combined with general anesthesia on postoperative immune and cognitive functions in elderly patients undergoing subtotal gastrectomy. We recruited 96 elderly patients who received anesthesia for subtotal gastrectomy and randomly divided them into control (n=48) and experimental (n=48) groups. The control group received general anesthesia and the experimental group received combined acupuncture and general anesthesia. We measured hemodynamic immediately before and after anesthesia induction, and immune observations before and after surgery. We found no significant differences in mean heart rate (HR), mean oxygen saturation (SpO2), and partial pressure of end-tidal carbon dioxide (PETCO2) in the perioperative period between the two groups. Mean arterial pressure (MAP) was lower in the experimental group than that in the control group (P<0.05). The levels of cluster of differentiation 3 (CD3+), CD4+ and CD4+/CD8+ in both groups were significantly lower after surgery in both groups (P<0.05). We also found some time-points in which the immune markers where significantly higher in the experimental group. In terms of adverse reactions, there were no differences in nausea, vomiting, and hypoxemia between the two groups (P>0.05), but the incidence of delayed recovery and postoperative agitation were significantly lower in the experimental group compared with those in the control group (P<0.05). One day after surgery, the experimental group showed better protection of cognitive function than the control group (P<0.05). Overall, combined acupuncture and general anesthesia in elderly gastric cancer patients receiving subtotal gastrectomy showed more stable hemodynamics and fewer stress responses during surgery. Thus, combined acupuncture and general anesthesia can shorten the recovery time from anesthesia, have less negative effects on immune function and decrease the incidence of postoperative cognitive impairment.

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Acupuncture accelerates recovery after general anesthesia: a prospective randomized controlled trial

Cited by 19 publications

References 18 publications

Electroacupuncture Ameliorates the Coronary Occlusion Related Tachycardia and Hypotension in Acute Rat Myocardial Ischemia Model: Potential Role of Hippocampus

Electroacupuncture Ameliorates the Coronary Occlusion Related Tachycardia and Hypotension in Acute Rat Myocardial Ischemia Model: Potential Role of Hippocampus

Acupuncture reduces the time from extubation to ‘ready for discharge’ from the post anaesthesia care unit: results from the randomised controlled AcuARP trial

Combined acupuncture and general anesthesia on immune and cognitive function in elderly patients following subtotal gastrectomy for gastric cancer

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