In this special issue, we define ableism as stereotyping, prejudice, discrimination, and social oppression toward people with disabilities-the largest minority group in the United States. People with disabilities are broadly defined as those who have conditions that are commonly perceived to be disabilities by the general public, including physical, sensory, and intellectual disabilities, in addition to invisible disabilities, chronic health conditions, psychiatric conditions, and others. Foundational work on language, stigma, models of disability, and social and rehabilitation psychology is reviewed. The issue has three areas of focus: social and individual-level predictors of ableism, experiences and consequences of ableism, and navigating and resisting ableism.