Activity-related pain in patients with chronic musculoskeletal disorders

Damsgård, Elin; Thrane, Gyrd; Anke, Audny; Fors, Terese; Røe, Cecilie

doi:10.3109/09638280903567877

Cited by 50 publications

(44 citation statements)

References 56 publications

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“…The duration of pain has been shown to be important, because subjects with a long pain duration experience more pain and lower life satisfaction than do subjects with a shorter pain duration (4). Furthermore, pain at rest may better differentiate between the global life satisfaction groups than pain during activity, although activity-related pain has been observed to be related to psychological distress (35). In addition, as observed in our analyses and not previously reported, the main difference in pain intensity was found between participants who were markedly dissatisfied (grades 1-3) and participants with higher global life satisfaction scores.…”

Section: Life Satisfaction and Pain Characteristicssupporting

confidence: 74%

“…The theoretically stable personality orientation SOC is known to change after certain events (19), and we propose that SOC may be negatively affected by persistently painful conditions, thereby reducing the subject's coping ability. The subjects' experience of control over the pain (SEP) is unsurprisingly positively associated with many life satisfaction items; however, SEP was most strongly correlated with satisfaction in the ability to perform daily activities, possibly because individuals with low self-efficacy more often experience increased pain during activity (35).…”

Section: Life Satisfaction and Demographic Factorsmentioning

confidence: 99%

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Life satisfaction in subjects with long-term musculoskeletal pain in relation to pain intensity, pain distribution and coping

Anke¹,

Damsgård²,

Røe³

2013

J Rehabil Med

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Objective: To investigate levels of life satisfaction in subjects with long-term musculoskeletal pain in relation to pain characteristics and coping. Design: Cross-sectional study. Methods: A total of 232 (42%) respondents answered selfreport questionnaires regarding life satisfaction, self-efficacy, sense of coherence, pain distribution and pain intensity at rest and during activity. Results: Levels of life satisfaction and scores for sense of coherence were low. Pain intensity at rest was negatively correlated with global life satisfaction. This result was also obtained in multiple regression analyses together with the coping factors. The life satisfaction domains activities of daily living/contacts were negatively correlated with pain intensity during activity, and the domains work/economy were negatively correlated with pain distribution. Pain was not associated with satisfaction with family life, partner relationship or sexual life. Younger age, being married/cohabitant and being female were protective for some domains. Clinically meaningful subgroups with regard to adaptation were identified by cluster analysis, and the highest level of coping was found in the adaptive cluster with high life satisfaction/low pain intensity at rest. Conclusion: Long-term pain is related to low levels of life satisfaction, and pain intensity and distribution influence satisfaction in different domains. Pain intensity is negatively associated with coping. The results support efforts to reduce pain, together with strengthening active coping processes and addressing individual needs.

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Section: Life Satisfaction and Pain Characteristicssupporting

confidence: 74%

Section: Life Satisfaction and Demographic Factorsmentioning

confidence: 99%

Life satisfaction in subjects with long-term musculoskeletal pain in relation to pain intensity, pain distribution and coping

Anke¹,

Damsgård²,

Røe³

2013

J Rehabil Med

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“…While exercise is an important component in managing musculoskeletal pain conditions[5, 9, 22, 53], it can enhance pain and hyperalgesia in chronic musculoskeletal pain conditions in humans and animals[14, 55, 57, 59]. An acute bout of exercise enhances hyperalgesia in sedentary mice, while regular physical activity prevents development of hyperalgesia[49, 56].…”

Section: Introductionmentioning

confidence: 99%

Short-duration physical activity prevents the development of activity-induced hyperalgesia through opioid and serotoninergic mechanisms

Lima

DeSantana

Rasmussen

et al. 2017

PAIN

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Regular physical activity prevents the development of chronic muscle pain through the modulation of central mechanisms that involve rostral ventromedial medulla (RVM). We tested if pharmacological blockade or genetic deletion of mu-opioid receptors in physically active mice modulates excitatory and inhibitory systems in the RVM in an activity-induced hyperalgesia model. We examined response frequency to mechanical stimulation of the paw, muscle withdrawal thresholds, and expression of phosphorylation of the NR1 subunit of the N-methyl-D-aspartate receptor (p-NR1) and serotonin transporter (SERT) in the RVM. Mice that had performed 5 days of voluntary wheel running prior to the induction of the model were compared with sedentary mice. Sedentary mice showed significant increases in mechanical paw withdrawal frequency and a reduction in muscle withdrawal threshold; wheel running prevented the increase in paw withdrawal frequency. Naloxone-treated and MOR−/− mice had increases in withdrawal frequency that were significantly greater than that in physically active control mice and similar to sedentary mice. Immunohistochemistry in the RVM showed increases in p-NR1 and SERT expression in sedentary mice 24 hours after the induction of the model. Wheel running prevented the increase in SERT, but not p-NR1. Physically active, naloxone-treated, and MOR−/− mice showed significant increases in SERT immunoreactivity when compared with wild-type physically active control mice. Blockade of SERT in the RVM in sedentary mice reversed the activity-induced hyperalgesia of the paw and muscle. These results suggest that analgesia induced by 5 days of wheel running is mediated by mu-opioid receptors through the modulation of SERT, but not p-NR1, in RVM.

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“…Increased muscle pain after exercise is a common phenomenon and pain may be used as an indicator of intensity of muscle usage [35]. High pain threshold and tolerance indicate a low sensitivity to pain, which may lead individuals with neck pain to inaccurately estimate their activity level.…”

Section: Discussionmentioning

confidence: 99%

“…These coping behaviors can be maladaptive and result in disability and disuse, leading to chronic pain [31]. Individuals with chronic musculoskeletal disorders and high kinesiophobia reported greater activity-associated pain and low levels of physical activity [35, 36]. In neck pain populations, measures of kinesiophobia are predictive of chronic disability and work capacity [32, 33, 37-39].…”

Section: Introductionmentioning

confidence: 99%

The Relationship Between Neck Pain and Physical Activity

Cheung¹,

Kajaks²,

MacDermid³

2013

TOORTHJ

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Neck pain is a significant societal burden due to its high prevalence and healthcare costs. While physical activity can help to manage other forms of chronic musculoskeletal pain, little data exists on the relationship between physical activity and neck pain. The purpose of this study was to compare physical activity levels between individuals with neck pain and healthy controls, and then to relate disability, fear of movement, and pain sensitivity measures to physical activity levels in each of the two participant groups. 21 participants were recruited for each of the two participant groups (n = 42). Data collection included the use of the Neck Disability Index, the Tampa Scale for Kinesiophobia, electrocutaneous (Neurometer® CPT) and pressure stimulation (JTech algometer) for quantitative sensory testing, and 5 days of subjective (Rapid Assessment of Physical Activity) and objective (BioTrainer II) measurements of physical activity. Analysis of Variance and Pearson’s Correlation were used to determine if differences and relationships exist between dependent variables both within and between groups. The results show that individuals with mild neck pain and healthy controls do not differ in subjectively and objectively measured physical activity. While participants with neck pain reported higher neck disability and fear of movement, these factors did not significantly relate to physical activity levels. Perceived activity level was related to pain threshold and tolerance at local neck muscles sites (C2 paraspinal muscle and upper trapezius muscle), whereas measured activity was related to generalized pain sensitivity, as measured at the tibialis anterior muscle site.

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Activity-related pain in patients with chronic musculoskeletal disorders

Cited by 50 publications

References 56 publications

Life satisfaction in subjects with long-term musculoskeletal pain in relation to pain intensity, pain distribution and coping

Life satisfaction in subjects with long-term musculoskeletal pain in relation to pain intensity, pain distribution and coping

Short-duration physical activity prevents the development of activity-induced hyperalgesia through opioid and serotoninergic mechanisms

The Relationship Between Neck Pain and Physical Activity

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