“…Furthermore, patulin causes impairment of kidney functions, oxidative damage, and weakness to the immune system. It also has a negative impact on reproduction in males via interaction with hormone production (Lima et al, 1998;Batta, 2001;Batta, 2003). The fungus can enter the fruit through natural openings, pedicel vascular system (Conway, 1992), lenticels, stem and the calyx ends (Holmes 2005;Snowdon, 1990), or directly through the cuticle and epidermis (Batta, 2001).…”