“…Thus, multiple factors have to be considered when investigating health-related quality of life in children with CHD 11 . Previous health-related quality of life studies in patients with CHD described psychological, 1 , 32 , 39 psychosocial, 5 , 24 , 30 and medical variables 29 , 40 separately and their impact on health-related quality of life as well as specific dimensions of health-related quality of life 5 10 , 27 , 28 , 31 , 32 , 34 , 41 , 42 Health-related quality of life, 33 , 43 , 44 emotional and psychological functioning, 42 and psychosocial adjustment were investigated as outcomes after different invasive treatments, 9 , 33 , 43 , 44 , 45 or patients with different diagnoses were compared 46 .…”