2018
DOI: 10.4314/ijbcs.v11i5.7
|View full text |Cite
|
Sign up to set email alerts
|

Activité antifalcémiante d’extraits de trois plantes médicinales du Bukina Faso: <i>Jatropha curcas</i>, <i>Khaya senegalensis</i> et <i>Dichrostachys cinerea</i>

Abstract: RESUMEDans cette étude, une évaluation rétrospective sur 3 ans de la prévalence de l'hémoglobine S dans le Centre médical urbain de Samadin a été faite. Ensuite, les effets d'extraits aqueux de trois plantes utilisées dans le traitement de la drépanocytose chez des malades ont été évalués. L'évaluation de prévalence sur les dossiers de malades ayant réalisé une électrophorèse sur les trois dernières années dans le centre donne 87% pour AS, 2,4% pour SS et 10,6% pour SC. Elle a été faite sur 2133 patients dont … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

0
5
0

Year Published

2018
2018
2023
2023

Publication Types

Select...
7

Relationship

1
6

Authors

Journals

citations
Cited by 8 publications
(6 citation statements)
references
References 3 publications
0
5
0
Order By: Relevance
“…The excellent antisickling activity of ZHm extracts is thought to be due to a combination of the effects of several factors including the presence of amino acids, polyphenols, and the antioxidant power of these extracts. According to (Nur et al, 2012;, 2017) [28,37] , the antioxidant properties of phenolic compounds present in plant extracts could prevent membrane lipid peroxidation and thus prevent erythrocyte lysis.…”
Section: Discussionmentioning
confidence: 99%
“…The excellent antisickling activity of ZHm extracts is thought to be due to a combination of the effects of several factors including the presence of amino acids, polyphenols, and the antioxidant power of these extracts. According to (Nur et al, 2012;, 2017) [28,37] , the antioxidant properties of phenolic compounds present in plant extracts could prevent membrane lipid peroxidation and thus prevent erythrocyte lysis.…”
Section: Discussionmentioning
confidence: 99%
“…In a state of hypoxia, the oxidative stress occurring during sickle cell disease could increase methemoglobin level in red blood cells and weakened free radicals defense system (Nur et al, 2011). Also, this increased methemoglobin level would decrease hemoglobin oxygen (Sawadogo et al, 2017;Kitadi et al, 2015). The reducing power could allow EDB and DDB to change the iron from Fe 3+ to Fe 2+ .…”
Section: Discussionmentioning
confidence: 99%
“…One of the reasons is that many diseases are treated successfully by plants (Kamanyi et al, 1995). Indeed, plants are source of natural bioactive molecules with antiinflammatory (Gonzalez et al, 2011), antimicrobial (Daglia, 2012), antiviral (Chavez et al, 2006), antisickling (Sawadogo et al, 2017;Kitadi et al, 2015;Akakpo et al, 2018), and antioxidant (Pandey & Rizvi, 2009;Diomandé et al, 2018) properties. The cost of patient care is not always affordable for lowincome populations.…”
Section: Introductionmentioning
confidence: 99%
“…This study purpose was to evaluate GC effects on the susceptibility of cardiac muscle subjected to chronic ischemia for 7 and 14 days. Indeed, it is well known that many African plants contain active compounds in various diseases treatment (Traore et al, 2004 ;Lagnika et al, 2005;(Sawadogo et al, 2017). Some of these herbs are effective in high blood pressure treatment because they contain antihypertensive compounds relaxing vessels via endothelium that releases compounds such as nitric oxide (NO), and in ischemia case, cardiac or arterial muscles may be impaired in endothelial function (Varin et al, 1999); there is sometimes a reduction in vascular tone.…”
Section: Introductionmentioning
confidence: 99%