Active sunscreen ingredients in Australia

Yap, Francis H.X.; Chua, Hock C.; Tait, Clare P

doi:10.1111/ajd.12597

Cited by 16 publications

(10 citation statements)

References 76 publications

(125 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As with previous reports, benzophenone‐3 demonstrated a high prevalence of positive photoallergic reaction (4.7%); this is because it has been frequently used as a photoprotective agent in sunscreens and personal care products 5,11,26,27 . However, positive photoallergic reactions to benzophenone‐3 in our participants mainly come from sunscreen.…”

Section: Discussionsupporting

confidence: 86%

Photopatch testing in a tropical country, Thailand: 20 years' experience

Chaiyabutr

Sukakul

Limphoka

et al. 2020

Photoderm Photoimm Photomed

View full text Add to dashboard Cite

Background: Photoallergic contact dermatitis is one of the important parts of photodermatoses. The investigation of choice is photopatch testing. However, reports with photopatch test results from Asian countries are scarce. The objective of this study was to determine the prevalence of positive photopatch test reactions and to ascertain the common photoallergens among Thai patients during 1998-2018. Methods: We retrospectively reviewed the records of 339 patients who were clinically suspected of having photoallergic contact dermatitis and had undergone photopatch testing. Results: A total of 44 photoallergic contact reactions in 38 patients (11.2%) were found. The positive photoallergic reactions were mainly found with organic ultraviolet filters and fragrances. Conclusions: Organic ultraviolet filter chemicals especially benzophenone-3 and fragrances were found to have a high prevalence of photoallergic contact reactions. Monitoring of the photoallergens employed in photopatch tests should be conducted periodically to provide the best patient care.

show abstract

Section: Discussionsupporting

confidence: 86%

Photopatch testing in a tropical country, Thailand: 20 years' experience

Chaiyabutr

Sukakul

Limphoka

et al. 2020

Photoderm Photoimm Photomed

View full text Add to dashboard Cite

show abstract

“…Exploring novel, safe, and effective photoprotective compounds is important because many existing optical protectants have some limitations due to their esthetics and the local skin reactions that they cause . Studies have shown that milk thistle and olive extracts prevent sun‐induced skin damage, while ellagic acid and rosmarinic acid could prevent damage due to UVB in HaCaT cells .…”

Section: Introductionmentioning

confidence: 99%

Cyanidin‐3‐o‐glucoside inhibits UVA‐induced human dermal fibroblast injury by upregulating autophagy

Bai

et al. 2019

Photoderm Photoimm Photomed

View full text Add to dashboard Cite

Background/Purpose Ultraviolet (UV) A (315‐400 nm) is the UV light that most frequently reaches the Earth's surface and can penetrate the epidermis through to the dermis, causing various issues, including skin aging and skin cancer. The results of our previous studies have shown that the flavonoid monomer cyanidin‐3‐o‐glucoside (C3G) can effectively inhibit primary human dermal fibroblast (HDF) oxidative damage and apoptosis caused by UVA radiation. Many flavonoids can regulate the level of autophagy. However, whether C3G inhibits UVA‐induced oxidative damage to primary HDFs by regulating autophagy levels remains unclear. Methods and Results In this study, we used different doses (0‐12 J/cm2) of UVA to irradiate cells and showed that the expression levels of autophagy‐related gene 5 (Atg5) and microtubule‐associated protein 1 light chain 3 (LC3)‐II in primary HDFs first increased and then decreased. The expression of Atg5 and LC3‐II was significantly decreased under 12 J/cm2 (light‐damage model). C3G increased the levels of Atg5 and LC3‐II. Primary HDFs were pretreated with C3G, followed by treatment with the autophagy inhibitor 3‐methyladenine (3‐MA) after 12 J/cm2 UVA irradiation. The inhibitory effects of C3G on morphological changes, oxidative damage, and apoptosis in primary HDFs induced by UVA were significantly decreased. Conclusion C3G can inhibit UVA‐induced damage to primary HDFs by inducing autophagy. These results provide a theoretical basis for the application of natural compounds to resist light damage to the skin in the future.

show abstract

“…The organic ingredients, such as avobenzone and octocrylene, are known to cause endocrine disruption and skin irritation. 9,10 Furthermore, these organic compounds are easily decomposed by UV rays, resulting in reduction of their UV-absorbing efficiency over time. 11 The inorganic ingredients, such as titanium dioxide (TiO 2 ) and zinc oxide (ZnO), are generally regarded as being safer than their organic counterparts for their biocompatibility, but they also have drawbacks, such as being opaque and photocatalytic.…”

Section: Introductionmentioning

confidence: 99%