Active microfluidic reactor-assisted controlled synthesis of nanoparticles and related potential biomedical applications

Abstract

Fabricating high-performance nanoparticles is currently a focus of researchers due to their manipulative size-dependent unique properties needed to develop next-generation advanced systems. To harness the unique properties of nanoparticles, maintaining...

Real-time assessment of the impacts of polystyrene and silver nanoparticles on the hatching process and early-stage development of Artemia using a microfluidic platform

“…PS, accounting for 23 million tons of annual global plastic production, 12 contributes significantly to marine debris. [13][14][15] Ag NPs are widely used in medical applications, 16 biosensors, 17 electronics, 18 textiles, 19 and more, posing water contamination risks due to their high toxicity. 20,21 While a large number of studies have focused on microparticles (MPs), [22][23][24][25] NPs may pose greater harm 26 due to size-related properties, enabling wider dispersal, 27,28 mistaken/incidental ingestion by marine life, 29,30 and prompt toxin release.…”

“…PS, accounting for 23 million tons of annual global plastic production, 12 contributes significantly to marine debris. 13–15 Ag NPs are widely used in medical applications, 16 biosensors, 17 electronics, 18 textiles, 19 and more, posing water contamination risks due to their high toxicity. 20,21…”

Real-time assessment of the impacts of polystyrene and silver nanoparticles on hatching process and early-stage development ofArtemiausing a microfluidic platform

“…PS nanoplastics are utilized in packaging and nanomedicine applications as well. Ag NPs are one of the most commonly used metallic nanoparticles in medical applications 32 , biosensors 33 , nano-enabled consumer electronics 34 , textiles and building facades, which may emit Ag NPs that end up in the water 35,36 and are highly toxic 37 . It is important to note that the behavior of MNPs in fresh and saltwater differs significantly.…”

“…Here, a zooplankton species, commonly used as live feed in marine finfish larviculture due to its small size and rich nutrient content 44,45 , Artemia franciscana, was used to examine the toxic effects of these two NPs on both the hatching process and nauplius stage. Previously, this species has been widely used as an aquatic model animal in ecological, ecotoxicological, genetic, biochemical, and physiological studies [33][34][35] . Previous comparative studies on the impacts of different NPs on Artemia focused primarily on the larval or adult stages [46][47][48][49][50][51][52] with few studies evaluating the impacts of different NPs on hatching rate (HR) [53][54][55][56] .…”

Enabling Smart Agriculture through Sensor-Integrated Microfluidic Chip to Monitor Nutrient Uptake in Plants

“…[5][6][7][8][9] Hence researchers need a low-cost real-time platform to understand various phenomena associated with plant germination, growth, metabolism, nutrient uptake, and survival. Advances in miniature, low-powered, wireless sensors together with nanoparticles and microfluidics have shown considerable promise for health, medicine, [10][11][12] microreactors, 13,14 and energy 15 and have now become a growing topic in agriculture as engineered synthetic ecosystems and recently have become popular in precision agriculture. [16][17][18][19][20] The high throughput of microfluidic platforms enables them to deliver microliters of fluid to specific outputs, making in situ monitoring of minute specimens possible.…”