Active compounds in kepok banana peel as anti-inflammatory in acne vulgaris: Review article

Anti-inflammatory effects of banana (Musa balbisiana) peel extract on acne vulgaris: In vivo and in silico study

“…In silico studies included searching for amino acids in the Toll-like receptor-2/nuclear factor-kappa B (TLR2/NF-κB) pathway and the structure of the active compound; protein 3D structure modeling; protein-ligand docking and visualization; and analysis of the binding interaction. We previously demonstrated that the phytochemical composition of MBPE includes trigonelline, vanillin, ferulic acid, isovanillic acid, rutin, and salsolinol, by using liquid chromatography-high resolution mass spectrometry 28 , 29 Subsequently, we performed an in silico study of TLR-2 and NF-κβ signals with molecular docking. The amino acid composition of the protein in the TLR2/NF-κβ pathway was obtained from the National Center for Biotechnology Information, United States National Library of Medicine, National Institutes of Health ( http://www.ncbi.nlm.nih.gov ).…”

The effects of systemic diseases, genetic disorders and lifestyle on keloids

“…Previous reports have also shown that chronic inflammation in acne patients predisposed by Propionibacterium acnes is associated with high risk of developing scars such as keloids, 60 Majorly by pathogenesis of androgeninduced increased sebum hyperproduction, altered follicular keratinization. 61,62 Viral infections Despite the lack of literature on viral infection involvement with the development of keloidal scars, some existing reports have demonstrated the possibility of herpes zoster lesions to heal with the formation of keloids on top of herpes zoster scar, which can be explained either as an isotopic phenomenon or presence of deeper, long standing herpes zoster lesions and development of secondary bacterial infection due to the long-term immunosuppressive therapy may be the other possible mechanisms of this keloids formation. 63…”

“…In the skin, M. leprae has an affinity for keratinocytes, macrophages, and histiocytes, 58 thus produces dermatological manifestations including keloids development occasionally in some types of leprosy such as Erythema Nodosum Leprosum (ENL), which results in cellular dysfunction as well as antigen–antibody complexes being deposited directly into tissues, 59 resulting in both acute nerve and skin inflammation, which is another predisposing cause to keloids. Previous reports have also shown that chronic inflammation in acne patients predisposed by Propionibacterium acnes is associated with high risk of developing scars such as keloids, 60 Majorly by pathogenesis of androgen‐induced increased sebum hyperproduction, altered follicular keratinization 61,62 …”

“…Previous reports have also shown that chronic inflammation in acne patients predisposed by Propionibacterium acnes is associated with high risk of developing scars such as keloids, 60 Majorly by pathogenesis of androgen‐induced increased sebum hyperproduction, altered follicular keratinization. 61 , 62 …”

Evaluation of Biogenic Silver Nanoparticles Synthesized from Vegetable Waste

“… 5 Banana peels are nowadays used to treat skin problems like irritations, allergies, acne, dark spots, and wrinkles in homemade remedies due to their strong antioxidant properties. 6 Stems of different vegetables, eg, coriander, are rich in nutrients having antimicrobial activities. Peels of potatoes are rich in dietary fiber, and a natural antioxidant is also discarded as a byproduct.…”