Active breathing control (ABC) for Hodgkin’s disease: reduction in normal tissue irradiation with deep inspiration and implications for treatment

Dosimetric Comparison of Three Different Involved Nodal Irradiation Techniques for Stage II Hodgkin's Lymphoma Patients: Conventional Radiotherapy, Intensity-Modulated Radiotherapy, and Three-Dimensional Proton Radiotherapy

“…Active breathing control devices might help to minimize the motion of mediastinal masses. Active breathing control devices have been studied in Hodgkin's lymphoma patients and shown to be tolerable, reproducible, and help in reducing the dose to the lung and heart (34,35). Currently, at the University of Florida Proton Therapy Institute, we account for respiratory motion when treating tumors in the chest by performing four-dimensional CT scan.…”

Reproducibility of lung tumor position and reduction of lung mass within the planning target volume using active breathing control (ABC)

“…The fatigue associated with repetitive breath holds may contribute to an uneven or inconsistent breathing pattern before each breath hold. It is likely that the ABC device may lead to better tumor/organ immobilization in patients with other malignancies who are fit and do not have compromised pulmonary function (15,19,20). Lastly, patients were asked to perform a breath hold at a comfortable inspiration volume, rather than at maximum inspiration or expiration.…”

“…Previous studies have described the device and quantified its ability to immobilize lung volumes and normal structures, such as diaphragm position (12,15,16). The main purpose of this study was to quantify the ability of the ABC device to immobilize peripheral lung tumors at a reproducible position from breath hold to breath hold.…”

RapidArc combined with the active breathing coordinator provides an effective and accurate approach for the radiotherapy of hepatocellular carcinoma

“…We compared FB, EIH, and EEH hold without using the end of deep inspiration hold (EDIH) or end of deep expiration hold (EDEH). First, greater mobility was investigated in the EDIH and EDEH, which may affect the location relationship between the liver and surrounding organs, thereby affecting the dose-volume relationship of OARs [37]. Second, the deep inspiration and expiration required good respiratory functions and the coordination ability of the patients.…”