Activators of viral gene expression in polarized epithelial monolayers identified by rapid-throughput drug screening

Sorscher, Eric J.; Harris, Jacqueline J.; Alexander, Michelle; Rottgers, A; Hardy, Kenneth J.; Ponnazhagan, Selvarangan; Collawn, James F.; McClintock, James B.; Amsler, Charles D.; Webster, A. D.; Maddry, Joseph A.; Baker, Bill J.; Hong, Jeong S.

doi:10.1038/sj.gt.3302676

Cited by 5 publications

(2 citation statements)

References 49 publications

(53 reference statements)

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“…Taken together, these studies demonstrate the importance of junctional proteins in the infectivity of viruses and suggest that they might impact the efficacy of the viral oncolytic gene therapies. Compounds could thus be identified for example to improve viral gene transfer [169].…”

Section: Desmosomes Adherens and Tight Junctions In Gene Therapymentioning

confidence: 99%

Targeting Intercellular Communication in Cancer Gene Therapy

Amessou¹,

Kandouz²

2013

Novel Gene Therapy Approaches

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Section: Desmosomes Adherens and Tight Junctions In Gene Therapymentioning

confidence: 99%

Targeting Intercellular Communication in Cancer Gene Therapy

Amessou¹,

Kandouz²

2013

Novel Gene Therapy Approaches

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“…Since hepatocyte growth factor is mitogenic, liver-directed gene transfer is a rational approach to treat liver cirrhosis [168]. To treat inherited gene deficiency diseases such as familial hypercholesterolemia (LDL receptor deficiency in hepatocytes) [169] and Crigler-Najjar syndrome (uridine diphospho-glucuronosyl transferase 1A1 deficiency in hepatocytes) [170], targeted gene delivery is also reasonable due to its efficacy.…”

Section: Disease-dependent Strategies In Targeted Gene Deliverymentioning

confidence: 99%

Novel Gene Therapy Approaches

Wei¹,

Good²

2013

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He is trained in clinical Medicine (MBBS), specialised on Microbiology (MSc., PhD) in China and Australia with further trainings in USA (Massachusetts Institute for Technology and University of Washington).He has an international reputation in gene delivery for gene therapy, especially cancer gene therapy with a focus on developing microbial vector systems. He was the secretary for Australasian Gene Therapy Society, served on National Health and Medical Research Council Grant Review Panel, is on the editorial boards of 14 international Journals, and reviews manuscripts and grants for many top journals and granting bodies internationally. He has won numerous awards, including the prestigious Dr Jain Zhou Smart State Fellow and has convened several national and international conferences. He has over 120 peer-reviewed publications.

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