Activation of the prefrontal cortex during the Trail‐Making Test detected with multichannel near‐infrared spectroscopy

Shibuya-Tayoshi, Sumiko; Sumitani, Satsuki; Kikuchi, Kumiko; Tanaka, Tsunehiko; Tayoshi, ShinʼYa; Ueno, Shu‐ichi; Ohmori, Tetsuro

doi:10.1111/j.1440-1819.2007.01727.x

Cited by 84 publications

(69 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Our results agree with recent studies by Shibuya-Tayoshi et al 25 and Nakahachi et al, 26 who found a bilateral O 2 Hb increase prefrontally. Interestingly, a widespread, powerful right HHb activation was constantly present in GLM maps throughout the test.…”

Section: Discussion Of Resultssupporting

confidence: 83%

“…23 Schreppel et al 24 investigated the effects of interference resolution processes on activation of the PFC in a WM task by means of fNIRS. Shibuya-Tayoshi et al 25 and Nakahachi et al 26 employed fNIRS devices to obtain a mapping of the activation of the PFC during the visuospatial WM Trail Making Test. They reported bilateral activation, primarily in the PFC.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Load-dependent brain activation assessed by time-domain functional near-infrared spectroscopy during a working memory task with graded levels of difficulty

et al. 2012

View full text Add to dashboard Cite

Abstract. We evaluated frontal brain activation during a mixed attentional/working memory task with graded levels of difficulty in a group of 19 healthy subjects, by means of time-domain functional near-infrared spectroscopy (fNIRS). Brain activation was assessed, and load-related oxy-and deoxy-hemoglobin changes were studied. Generalized linear model (GLM) was applied to the data to explore the metabolic processes occurring during the mental effort and, possibly, their involvement in short-term memorization. GLM was applied to the data twice: for modeling the task as a whole and for specifically investigating brain activation at each cognitive load. This twofold employment of GLM allowed (1) the extraction and isolation of different information from the same signals, obtained through the modeling of different cognitive categories (sustained attention and working memory), and (2) the evaluation of model fitness, by inspection and comparison of residuals (i.e., unmodeled part of the signal) obtained in the two different cases. Results attest to the presence of a persistent attentional-related metabolic activity, superimposed to a task-related mnemonic contribution. Some hemispherical differences have also been highlighted frontally: deoxy-hemoglobin changes manifested a strong right lateralization, whereas modifications in oxy-and total hemoglobin showed a medial localization. The present work successfully explored the capability of fNIRS to detect the two neurophysiological categories under investigation and distinguish their activation patterns.

show abstract

Section: Discussion Of Resultssupporting

confidence: 83%

Section: Introductionmentioning

confidence: 99%

Load-dependent brain activation assessed by time-domain functional near-infrared spectroscopy during a working memory task with graded levels of difficulty

et al. 2012

View full text Add to dashboard Cite

show abstract

“…These are the regions that most likely underlie cognitive flexibility during the TMT and are candidate regions underlying the impairment of groups with poor set-shifting abilities. These results are consistent with those presented in these studies [18] [19] [20].…”

Section: Neuroanatomical Correlatessupporting

confidence: 83%

The Trail Making Test in Morocco: Normative Data Stratified by Age and Level of Education

Oumellal¹,

Faris²,

Benabdeljlil³

2018

OJMP

View full text Add to dashboard Cite

The purpose of this study is to design a Moroccan Trail Making Test B; explore the effects of age, education and gender on the performance of the Trail Making Test (TMT); and provide normative information in Moroccan subjects. Our normalization study was conducted on 348 subjects (156 female and 192 male). The subjects were classified into four groups based on age (18 -39 years, 40 -59 years, 60 -69 years and ≥70 years), and three groups based on educational level (3 -6 years, 7 -10 years and ≥11 years). The data were analyzed using descriptive statistics through SPSS. The results displayed that increasing age and decreasing levels of education significantly result in a decreased performance on the Trail A, Moroccan Trail B and English Trail B. Only 229 bilingual subjects among the 348 initial subjects completed both versions of Trail B. There was no significant difference on performance between Moroccan Trail B and English Trail B for these subjects.

show abstract

“…NIRS and fMRI are non-invasive methods for measuring brain activity. In studies using fMRI measurements, brain activity was mainly detected in the frontal lobe during TMT performance (Moll et al 2002;Zakzanis et al 2005), and in NIRS measurement, frontal lobe activity was also noted during TMT performance (Shibuya-Tayoshi et al 2007;Shoji et al 2009). A difference in NIRS measurements during TMT performance was noted in a comparison of normal children and children with attention-deficit hyperactivity disorder (Weber et al 2005).…”

mentioning

confidence: 99%

Identification of Three Factors Influencing Trail Making Test Performance Using Multichannel Near-Infrared Spectroscopy

Chie

Notoya

Sunahara

et al. 2011

Tohoku J. Exp. Med.

View full text Add to dashboard Cite

Recent advances in medical care have facilitated the survival of patients with stroke or traffic-related injuries. However, such patients may suffer from higher brain dysfunction; i.e., an impaired ability to plan and perform behaviors based on prior knowledge. The Trail Making Test (TMT) is a cognitive task that is used to evaluate higher brain dysfunction caused by frontal lobe injury. TMT consists of two tasks; TMT-A involves connecting consecutive numbers, and TMT-B involves connecting numbers and letters alternately. In this study, using near-infrared spectroscopy (NIRS) and the achievement value (TMT score), we investigated the effects of three factors on TMT performance: knowledge of the TMT, the order of TMT-A and TMT-B performance, and gender. The subjects were 48 healthy adults, consisting of college graduates and undergraduates (age: 22.8 ± 2.5 years, education: 16.0 ± 1.2 years, 24 males and 24 females). We measured the changes in oxygenated hemoglobin (oxy-Hb) levels using NIRS, showing that the increase in oxy-Hb was higher in subjects who had no knowledge of the TMT than those who had prior knowledge. In both TMT-A and TMT-B, the subjects who performed their first task displayed higher oxy-Hb levels. Moreover, the oxy-Hb level in males was higher than that in females. In contrast, only the order of TMT performance showed noticeable effect on the TMT score. In the present study, using NIRS we have shown that either knowledge of the TMT, the order of the TMT, or gender affects TMT performance, providing invaluable information for interpreting TMT results.

show abstract

Activation of the prefrontal cortex during the Trail‐Making Test detected with multichannel near‐infrared spectroscopy

Cited by 84 publications

References 24 publications

Load-dependent brain activation assessed by time-domain functional near-infrared spectroscopy during a working memory task with graded levels of difficulty

Load-dependent brain activation assessed by time-domain functional near-infrared spectroscopy during a working memory task with graded levels of difficulty

The Trail Making Test in Morocco: Normative Data Stratified by Age and Level of Education

Identification of Three Factors Influencing Trail Making Test Performance Using Multichannel Near-Infrared Spectroscopy

Contact Info

Product

Resources

About