Activation of somatostatin interneurons in the medial amygdala reverses long-term aggressive behavior associated to early-life stress in male mice
Esther Castillo-Gómez,
Aroa Mañas-Ojeda,
José Hidalgo-Cortés
et al.
Abstract:Early postnatal development is a critical period for the configuration of neural networks that support emotional and socio-affective behaviors. In this sense, children raised in stressful environments are at high risk of developing maladaptive behaviors immediately or later in life, including anti-social and aggressive behaviors. However, the neurobiological bases of such phenomena remain poorly understood. Here we showed that, at long-term, maternal separation with early weaning (MSEW) decreased the density o… Show more
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