Activation of Promutagens by Green Plants

Induction of Mutation in Drosophila melanogaster fed a hexane extract of vegetables grown in soil contaminated with particulates from diesel engine exhaust

“…Furthermore, most of the hexane extracts contained some green pigments, which were probably chlorophylls. The weak mutagenicity or absence of mutagenicity of some samples may due to the antimutagenicity of chlorophyll against diesel exhaust mutagens absorbed by such plants or to the metabolic detoxification pathway of the plant, as suggested by others [1,2].…”

“…Plants, especially food plants, are exposed to a wide variety of contaminants and may be considered as a "green liver," acting as an important global sink for environmental chemicals [1] that are of public health concern. Plewa and Wagner [2] stated that plants could activate promutagens and store the products in forms that might induce mutations in Induction of mutation in Drosophila melanogaster fed a hexane extract of vegetables grown in soil contaminated with particulates from diesel engine exhaust Kaew Kangsadalampai, Prapasri Laohavechvanich, and Janpen Saksitpitak…”

Les peroxydases végétales de classe III

“…Neanmoins, l'activite de peroxydases vacuolaires a ete reliee a Ia degradation de Ia chlorophylle lors de Ia senescence (Yamauchi & Watada, 1991 ;Funamoto eta/., 2003). De Ia meme maniere, les peroxydases semblent responsables de Ia degradation des capsalcinoldes, molecules responsables du gout epice, lors de Ia senescence chez le Piment (Contreras & Yahia, 1998 (Plewa & Wagner, 1993), mais elles sont aussi proposees comme un nouveau traitement possible contre le cancer en utilisant Ia specificite de I' oxydation de ! 'AlA par les peroxydases et Ia generation d'0 2 •-qui en decoule pour cibler et tuer specifiquement les cellules tumorales.…”

Assessment of Duguetia furfuracea genotoxic and cytotoxic activity in bacteria and mice

“…A large number of plants have been screened as viable sources of a variety of Anais da Academia Brasileira de Ciências (2012) in folk medicine are limited (Ruiz et al 1996). Green plants in general contain mutagenic and carcinogenic substances (Pimenta and Nepomuceno 2005, Sandermann Junior 1988, Velemi'nsky' and Gichner 1988, Kanaya et al 1992, Plewa and Wagner 1993, but there is little information on the biological effects of the compounds present in these plant species (Pimenta andNepomuceno 2005, Basaran et al 1996). Therefore it is of vital importance to evaluate the genotoxic and cytotoxic effects of phytotherapeutic substances since their usage has major impacts on the health of a large number of people (Marques et al 2003).…”