Abstract:Background: It has been reported that the NF-κB pathway, an important component of host defense system against pathogens infections, can be modulated by GRA15 of type 2 Toxoplasma gondii strains. A newly reported Toxoplasma strain (T.gHB1) belonging to type 1 showed polymorphic phenotypes comparable to the classic type 1 parasite, such as virulence determinant mechanisms. Therefore, it is worth investigating whether the novel type 1 Toxoplasma strain (T.gHB1) has an effect on host NF-κB signaling pathway.Metho… Show more
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