Activation of inducible nitric oxide synthase by Yongdam-Sagan-Tang in mouse peritoneal macrophages

Lee, E.H; Kim, N.K; Hwang, Chung‐Yeon; Kim, H.M

doi:10.1016/s0378-8741(97)00132-3

Cited by 13 publications

(2 citation statements)

References 39 publications

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“…Production of TNF-¬ protein is enhanced by the presence of interferon-® (IFN-®). TNF-¬ acts as an autocrine signal to amplify IFN-®-induced production of NO in macrophages (Lee et al 1998).…”

Section: Introductionmentioning

confidence: 99%

Water extract isolated fromChelidonium majusenhances nitric oxide and tumour necrosis factor-α production via nuclear factor-κB activation in mouse peritoneal macrophages

Chung

Jeong

et al. 2004

Journal of Pharmacy and Pharmacology

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Chelidonium majus is used to treat several inflammatory diseases and tumours. We have examined the effect of C. majus on nitric oxide (NO) production using mouse peritoneal macrophages. When C. majus was used in combination with recombinant interferon-gamma (rIFN-gamma, 10 U mL(-1)), there was a marked cooperative induction of NO production. Treatment of rIFN-gamma plus C. majus (1 mgmL(-1)) in macrophages caused a significant increase in tumour necrosis factor-alpha (TNF-alpha) production. The increased production of NO and TNF-alpha from rIFN-gamma plus C. majus-stimulated cells was almost completely inhibited by nuclear factor-kappaB (NF-kappaB) inhibitor, pyrrolidine dithiocarbamate (100 microM). These findings demonstrated that C. majus increased the production of NO and TNF-alpha by rIFN-gamma-primed macrophages and suggested that NF-kappaB played a critical role in mediating the effects of C. majus.

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Section: Introductionmentioning

confidence: 99%

Water extract isolated fromChelidonium majusenhances nitric oxide and tumour necrosis factor-α production via nuclear factor-κB activation in mouse peritoneal macrophages

Chung

Jeong

et al. 2004

Journal of Pharmacy and Pharmacology

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“…Decoction is the traditional method of oriental medicinal plant (OMP) extracts (Yondam‐Sagan‐Tang, Gamcho‐Sasim‐Tang, Du‐Shen‐Tang and so on) have been traditionally used as a tonic and a panacea that promotes longevity in Korea (Lee et al . 1998; Kim et al .…”

Section: Introductionmentioning

confidence: 99%

The effects of replacement of antibiotics with by‐products of oriental medicinal plants on growth performance and meat qualities in fattening pigs

Kang¹,

Chu²,

Song

et al. 2011

Animal Science Journal

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The effect of by-products of oriental medicinal plants (OMP; T1) containing 0.03% herb extracts (T2) or 0.1% aminolevulinic acid (T3) on the production performance of swine during the finishing period and on its meat quality were investigated. No significant differences were found in the weight gain, feed intake and feed conversion rate among the tested groups (P > 0.05). But the treated group showed higher (P < 0.05) moisture and ash and lower protein than the control group. The T3 group showed a lower meat cholesterol content (38.42 mg/100 g) compared to the other groups (P < 0.05). The vitamin E content of the muscle in the treated groups was higher compared to the control group. No antibiotic content was detected in all treated and control samples. The values of the volatile basic nitrogen (VBN) and thiobarbituric acid reactive substance (TBARS) of the treated groups were significantly lower (P < 0.01) than the control group. The treated groups had significantly better (P < 0.05) sensory-test scores for color, flavor, off-flavor and total acceptability compared to the control group.

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Effect of Se-Yeon-Eum on nitric oxide and tumor necrosis factor-α production in C6 glial cells induced by recombinant interferon-γ and cigarette extract

Lee

Jin

Lee

et al. 2017

Orient Pharm Exp Med

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Activation of inducible nitric oxide synthase by Yongdam-Sagan-Tang in mouse peritoneal macrophages

Cited by 13 publications

References 39 publications

Water extract isolated fromChelidonium majusenhances nitric oxide and tumour necrosis factor-α production via nuclear factor-κB activation in mouse peritoneal macrophages

Water extract isolated fromChelidonium majusenhances nitric oxide and tumour necrosis factor-α production via nuclear factor-κB activation in mouse peritoneal macrophages

The effects of replacement of antibiotics with by‐products of oriental medicinal plants on growth performance and meat qualities in fattening pigs

Effect of Se-Yeon-Eum on nitric oxide and tumor necrosis factor-α production in C6 glial cells induced by recombinant interferon-γ and cigarette extract

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