1979
DOI: 10.1007/bf00238051
|View full text |Cite
|
Sign up to set email alerts
|

Activation of human T-lymphocytes

Abstract: Stereological data of phytohaemagglutinin (PHA)-activated human T-lymphocytes were recorded at intervals (12 to 72 h) together with biochemical (isotope-uptake, lymphotoxin-release) and morphological measurements. About 98% of the cells were activated 12 h after PHA-stimulation. The activation phase lasted less than 48 h, i.e., cells entering the activation phase within 12 h were at their activation maximum by 48 h. The activated cell increased in size. The nuclear/cytoplasmic-ratio decreased. Most of the cyto… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

1
6
0
1

Year Published

1984
1984
2021
2021

Publication Types

Select...
4
2

Relationship

0
6

Authors

Journals

citations
Cited by 36 publications
(8 citation statements)
references
References 25 publications
1
6
0
1
Order By: Relevance
“…In the current study we find that the activated human T cells enlarge upon activation which is a well described feature in the activated and proliferating T cells [28,29]. There is a strong up-regulation of KCNK5 which is in agreement with earlier findings [8,23].…”
Section: Discussionsupporting
confidence: 82%
“…In the current study we find that the activated human T cells enlarge upon activation which is a well described feature in the activated and proliferating T cells [28,29]. There is a strong up-regulation of KCNK5 which is in agreement with earlier findings [8,23].…”
Section: Discussionsupporting
confidence: 82%
“…On the other hand, stronga cids (e.g.,m ethanesulfonic acid, trifluoroacetic acid, or p-TsOH) under reflux provide D 8À -THC (8)a samain product. [144][145][146] The formation of 8 could be via CBD as an intermediate, since (À)-2 can undergo intramolecular cyclization in the presence of p-TsOH. 121 Moreover,R azdane tal.…”
Section: Alkylation Of Chiralt Erpenesmentioning
confidence: 99%
“…[123] In the first step, the authors synthesized 44 through aF riedel-Crafts reaction between 26 and 43 using BF 3 •OEt 2 as ac at-Scheme13. Susceptibilityo fC BD synthesis to reaction conditions: a) oxalic acid, CHCl 3 ,208C, 66 h, (À)-2 (24 %); [121] b) p-TsOH,t oluene, RT,1.5 h, (À)-2 (20 %); [143,150] c) p-TsOH, benzene, 80 8C, 1.5 h, 8 (53 %); [146,151] 4 ,08C, (À)-1 (50 %); [143] e) 1) 8,ZnCl 2 ,HCl, CH 2 Cl 2 ,2 )K-t-amylate, benzene, 5t o6 58C, (À)-1 (92 %); [147] f) p-TsOH, benzene, 80 8C, 1.5 h, 8 (99 %). [114,121] Scheme14.…”
Section: Variation Of the Petrzilkaapproachmentioning
confidence: 99%
See 2 more Smart Citations