Activation of Brain Sensorimotor Network by Somatosensory Input in Patients with Hemiparetic Stroke: A Functional MRI Study

Kato, Harubumi; Izumiyama, Masahiro

doi:10.5772/51693

Cited by 4 publications

(4 citation statements)

References 71 publications

(80 reference statements)

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“…This result is consistent with previous neuroimaging studies on stroke showing that cortical motor connectivity can reflect poststroke sensorimotor signal processing ( 5 , 49 , 50 ). The SMA has strong anatomical connections with the areas of the central nervous system, including the thalamus, spinal cord, dorsal premotor cortex, and contralateral hemisphere regions ( 51 , 52 ). In stroke patients with subcortical injuries, the functional ability of the brain enabled by exchanges and cooperation between the two sides of the hemisphere is affected, and motor function is also influenced ( 49 ).…”

Section: Discussionmentioning

confidence: 99%

Aberrant interhemispheric functional reciprocities of the default mode network and motor network in subcortical ischemic stroke patients with motor impairment: A longitudinal study

Zhou

et al. 2022

Front. Neurol.

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PurposeThe purpose of the present study was to explore the longitudinal changes in functional homotopy in the default mode network (DMN) and motor network and its relationships with clinical characteristics in patients with stroke.MethodsResting-state functional magnetic resonance imaging was performed in stroke patients with subcortical ischemic lesions and healthy controls. The voxel-mirrored homotopic connectivity (VMHC) method was used to examine the differences in functional homotopy in patients with stroke between the two time points. Support vector machine (SVM) and correlation analyses were also applied to investigate whether the detected significant changes in VMHC were the specific feature in patients with stroke.ResultsThe patients with stroke had significantly lower VMHC in the DMN and motor-related regions than the controls, including in the precuneus, parahippocampus, precentral gyrus, supplementary motor area, and middle frontal gyrus. Longitudinal analysis revealed that the impaired VMHC of the superior precuneus showed a significant increase at the second time point, which was no longer significantly different from the controls. Between the two time points, the changes in VMHC in the superior precuneus were significantly correlated with the changes in clinical scores. SVM analysis revealed that the VMHC of the superior precuneus could be used to correctly identify the patients with stroke from the controls with a statistically significant accuracy of 81.25% (P ≤ 0.003).ConclusionsOur findings indicated that the increased VMHC in the superior precuneus could be regarded as the neuroimaging manifestation of functional recovery. The significant correlation and the discriminative power in classification results might provide novel evidence to understand the neural mechanisms responsible for brain reorganization after stroke.

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Section: Discussionmentioning

confidence: 99%

Aberrant interhemispheric functional reciprocities of the default mode network and motor network in subcortical ischemic stroke patients with motor impairment: A longitudinal study

Zhou

et al. 2022

Front. Neurol.

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“…Passive somatosensory stimulation techniques can be applied daily to stroke patients with complete paralysis. [ 22 ]…”

Section: Introductionmentioning

confidence: 99%

“…Passive somatosensory stimulation techniques can be applied daily to stroke patients with complete paralysis. [22] Passive somatosensory stimulation includes modalities that passively stimulate sensory receptors such as neuromuscular electrical stimulation, [19] transcutaneous electrical nerve stimulation (TENS), [19,23] intermittent pneumatic compression, [24] and thermal stimulation (TS). [25][26][27] Intermittent compression technique, a neurophysiological treatment involves stimulation of cutaneous and proprioceptive receptors by repeated movements.…”

Section: Introductionmentioning

confidence: 99%

Effect of compressive therapy on sensorimotor function of the more affected upper extremity in chronic stroke patients: A randomized clinical trial

et al. 2022

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Background: Common upper extremity (UE) physical impairments after stroke include paresis, abnormal muscle tone, and somatosensory affection. This study evaluated the effect of passive somatosensory stimulation using compressive therapy on sensorimotor function of the more affected UE in chronic stroke patients.Methods: Forty chronic stroke patients were enrolled in this study. They were randomized into 2 groups: Gr1 and Gr2. Three patients dropped out leaving us with a total of 37 patients completing the study. Gr1 received UE motor program for the more affected UE along with sham electrical stimulation while Gr2 had the same UE motor program along with passive somatosensory stimulation. The session duration in both groups was 85 min. Gr1 and Gr2 received a total of 36 sessions for 6 successive weeks. UE function in Gr1 and Gr2 was examined, before and after treatment using Box and Block test (BBT) and Perdue Pegboard test (PPBT) as measures of motor of both the more affected and less affected UE while the Nottingham sensory assessment (NSA) scale was used as a measure of sensory function of the more affected UE.Results: There were significant improvements in motor and sensory function of the more affected UE compared to the less affected UE in both groups, measured by the BBT, PPBT, and NSA scales post-treatment (P < .05). However, the comparison between both groups regarding improvement revealed no significant change (P > .05). Conclusion:Upper extremity motor and passive somatosensory stimulation techniques are effective in improving sensorimotor function of the more affected UE, but none of them had the advantage over the other, in terms of improving motor and sensory function in chronic stroke patients.

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“…Hemiparesis, paralysis, weakness, abnormal muscle tone, spasm, abnormal postures, abnormal function of synergic muscles, and loss of interjoint coordination are the most common injuries due to damage to the motor cortex. 5 Out of eighty percent of patients who experience acute upper extremity paresis after stroke, only one third reach full recovery of their function. 6 , 7 Those patients with longer period of disability need to be cared for by a caregiver who is most often a family member.…”

Section: Introductionmentioning

confidence: 99%

The Effect of Early Passive Range of Motion Exercise on Motor Function of People with Stroke: a Randomized Controlled Trial

2019

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Introduction: Frequent and regular exercises in the first six months of stroke may cause return of a significant portion of sensory and motor function of patients. This study aimed to examine the effects of passive range of motion exercise in the acute phase after stroke on motor function of the patients. Methods: A randomized controlled trial study was conducted. The patients with first ischemic stroke were randomly allocated to either experimental (n=33) or control (n=19) group. Passive range of motion exercises was performed in the experimental group during the first 48 hours of admission as 6 to 8 times of 30 minute exercise. Before intervention, and one and three months after intervention, motor function were measured by muscle strength grading scale (Oxford scale) and compared. SPSS version 13.0 for Windows was used for statistical analysis. Frequency distribution was used to describe the data. For comparisons, paired t-test, independent t-test was used, and repeated measures test was used. Results: In acute phase, the intervention in the experimental group led to significant improvement of motor function between the first and third month in both the upper and lower extremities. In control group, improvement was observed only in the muscle strength of upper extremity in the first and third month compared to pre-intervention measurement. The greatest improvement was observed in the interval from base to one month in the upper extremity, and base to the first month and the first to the third month in the lower extremity. Conclusion: It is recommended to use early passive range of motion exercise as part of care for people with stroke during the acute phase of the disease.

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Activation of Brain Sensorimotor Network by Somatosensory Input in Patients with Hemiparetic Stroke: A Functional MRI Study

Cited by 4 publications

References 71 publications

Aberrant interhemispheric functional reciprocities of the default mode network and motor network in subcortical ischemic stroke patients with motor impairment: A longitudinal study

Aberrant interhemispheric functional reciprocities of the default mode network and motor network in subcortical ischemic stroke patients with motor impairment: A longitudinal study

Effect of compressive therapy on sensorimotor function of the more affected upper extremity in chronic stroke patients: A randomized clinical trial

The Effect of Early Passive Range of Motion Exercise on Motor Function of People with Stroke: a Randomized Controlled Trial

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