Activated carbon fibers/poly(lactic-co-glycolic) acid composite scaffolds: Preparation and characterizations

Preparation and Properties of Bamboo Fiber/Nano-hydroxyapatite/Poly(lactic-co-glycolic) Composite Scaffold for Bone Tissue Engineering

“…To achieve the high mechanical property of n-HA/PLGA composite scaffold, polymeric composites reinforced with fibers are widening application fields, including construction trade and automotive business. 21 In the past years, some researchers have been concentrating on probing natural fibers as reinforcement in composite, such as kenaf, hemp, jute, and flax, which was combined with biodegradable polymers, so as to obtain a new kind of entirely biodegradable "green" composites. 22−25 nally arranged in the culm, and the mechanical properties produced by BF can rival glass fibers, so BF has the reputation of "natural glass fibers".…”

“…Based on the biomimetic point of view, it has been suggested that nano-hydroxyapatite (n-HA) may be an ideal filler due to its chemical component similarity and crystal analogy with bone mineral, which has osteoconductive properties and a prominent osseointegration, so that it could potentially improve both biocompatibility and bone integration ability. − Accordingly, n-HA/PLGA composite scaffold is a promising candidate for bone tissue regeneration. − However, the improvement of mechanical strength and degradation of n-HA/PLGA composite scaffold remained as a crucial challenge. To achieve the high mechanical property of n-HA/PLGA composite scaffold, polymeric composites reinforced with fibers are widening application fields, including construction trade and automotive business . In the past years, some researchers have been concentrating on probing natural fibers as reinforcement in composite, such as kenaf, hemp, jute, and flax, which was combined with biodegradable polymers, so as to obtain a new kind of entirely biodegradable “green” composites. − Similarly, bamboo fibers (BFs) are longitudinally arranged in the culm, and the mechanical properties produced by BF can rival glass fibers, so BF has the reputation of “natural glass fibers”. , Therefore, BF is good for reinforcement of plastic, rubber, and biopolymer matrices, and it has been widely used in the polymer composite industry. − Based on our former study, we concluded that the surface-treated bamboo fiber could enhance the mechanical properties of the n-HA/PLGA composite, and a novel biodegradable BF/n-HA/PLGA ternary composite was achieved .…”

对氨基苯甲酸掺杂的微槽结构碳纤维用于改善pla-Peg的强度及生物相容性

“…The modification with HNO3 route followed the similar way as mentioned above. The scaffold samples were prepared based on solvent casting/particle leaching method according to our previous study [17]. Pure PLA-PEG scaffolds and their composite scaffolds modified with 0.5 and 2.0 wt.% CFs or PABA treated CFs were prepared, respectively.…”

“…PABA modification produces many micro-grooves serving as defect sites over CFs surfaces because of the acidic solution etching, and such defect sites containing hydrophilic groups can share the mechanical load based on defect theory, especially when banding with other matrixes [37]. Robust combination between the modified CFs and matrix is the essential precondition for optimizing the mechanical properties of scaffolds [17], which is largely subjected to each component's surface status. Compared with the untreated CFs (depicted as Control CFs), PABA-CFs provide rougher surface for hydrophilic groups such as -COOH to graft on, which is proved by FT-IR spectra.…”

“…In order to address the above mentioned concerns in obtaining maximum performance of CFs in the polymer matrix, we first introduced para-amino benzoic acid (PABA) as a surface modification agent to improve CFs' surface status as well as micro-grooved patterns. Our rationality is based on the following considerations: (1) PABA is a kind of folic acid related small molecule, which can be used as a moderate acidic modification agent [16]; (2) CFs of excellent mechanical performance are potential reinforcement for scaffold materials [15,17].…”